Sugi Predict

Sugi Predict / Compounds / SCHEMBL979718

SCHEMBL979718

SCHEMBL979718

O=C1C(=Cc2ccccc2)COc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 16/20 1.00
▸ MIF P14174 2/20 0.78
▸ MEN1 O00255 1/20 0.78
▸ ACHE P22303 1/20 0.78
▸ KMT2A Q03164 1/20 0.78
▸ TDP1 Q9NUW8 1/20 0.78
▸ APP P05067 1/20 0.69
▸ MAOA P21397 2/20 0.68
▸ MITF O75030 1/20 0.63
▸ ALDH1A1 P00352 1/20 0.63
▸ LMNA P02545 1/20 0.63
▸ MAPT P10636 1/20 0.63
▸ HTT P42858 1/20 0.63
▸ SMN1; SMN2 Q16637 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31179771 1.00 MAOB (1.00) MAOBMIFMEN1ACHEKMT2A
SCHEMBL979717 1.00 MAOB (1.00) MAOBMIFMEN1ACHEKMT2A
SCHEMBL29595747 1.00 MAOB (1.00) MAOBMIFMEN1ACHEKMT2A
SCHEMBL9635332 0.88 MAOB (1.00) MAOBMIFMEN1ACHEKMT2A
SCHEMBL9635329 0.88 MAOB (1.00) MAOBMIFMEN1ACHEKMT2A
SCHEMBL18836413 0.84 MAOB (1.00) MAOBMIFMEN1ACHEKMT2A
SCHEMBL25502260 0.84 MAOB (0.72) MAOBMIFMEN1ACHEKMT2A
SCHEMBL13708801 0.84 MAOB (1.00) MAOBMIFMEN1ACHEKMT2A
SCHEMBL13299560 0.84 MAOB (1.00) MAOBMIFMEN1ACHEKMT2A
SCHEMBL13708805 0.82 MAOB (0.71) MAOBMIFMEN1ACHEKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190142792-A1 ANTIVIRAL EPICATECHINS, EPICATECHIN OLIGOMERS, OR THIOLATED EPICATECHINS FROM THEOBROMA CACAO FOR TREATMENT OF GENITAL WARTS CACAO BIO-TECHNOLOGIES, LLC (US) 2019-05-16 — — US claimed
US-20170035726-A1 ANTIVIRAL EPICATECHINS, EPICATECHIN OLIGOMERS, OR THIOLATED EPICATECHINS FROM THEOBROMA CACAO FOR TREATMENT OF GENITAL WARTS CACAO BIO-TECHNOLOGIES, LLC (US) 2017-02-09 — — US claimed
US-20150011488-A1 ANTIVIRAL EPICATECHINS, EPICATECHIN OLIGOMERS, OR THIOLATED EPICATECHINS FROM THEOBROMA CACAO FOR TREATMENT OF GENITAL WARTS CACAO BIO-TECHNOLOGIES, LLC (US) 2015-01-08 — — US claimed
US-20110218241-A1 ANTIVIRAL EPICATECHINS, EPICATECHIN OLIGOMERS, OR THIOLATED EPICATECHINS FROM THEOBROMA CACAO FOR TREATMENT OF GENITAL WARTS CACAO BIO-TECHNOLOGIES, LLC (US) 2011-09-08 — — US claimed
CN-107334760-B Simultaneously chromanone is preparing the application in anticarcinogen to 7- benzal dihydrofuran 湖南大学 2019-08-16 — — CN disclosed
CN-107098916-B 7- (pyridine methylene) dihydrofuran and chromanone and the preparation method and application thereof 湖南大学 2019-04-12 — — CN disclosed
CN-105541859-B Dihydrofuran and chromanone derivatives and preparation method thereof and medical usage 湖南大学 2017-12-29 — — CN disclosed
CN-107334760-A 7 benzal dihydrofuran and application of the chromanone in anticarcinogen is prepared 湖南大学 2017-11-10 — — CN disclosed
CN-107098916-A 7‑（Pyridine methylene）Dihydrofuran and chromanone and preparation method and application 湖南大学 2017-08-29 — — CN disclosed
CN-104211642-A Synthesis of dihydropyrazol sulfanilamide derivatives containing tetrahydronaphthalene or chroman framework and application of derivatives in anti-cancer drugs NANJING UNIVERSITY OF TECHNOLOGY 2014-12-17 — — CN disclosed
US-7872029-B2 Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states BOWEN J PHILLIP 2011-01-18 — — US disclosed
US-20090018167-A1 Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states Robinson, Thomas Philip (US) 2009-01-15 — — US disclosed
EP-0902003-B1 NOVEL TETRALONE OR BENZOPYRANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME DAIICHI SEIYAKU CO (JP) 2006-07-26 — — EP disclosed
US-20050148599-A1 Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2005-07-07 — — US disclosed
US-6906105-B2 Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states BOWEN J PHILLIP (US) 2005-06-14 — — US disclosed
US-20030027830-A1 Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2003-02-06 — — US disclosed
US-6462075-B1 USE OF CHALCONE AND ITS DERIVATIVES AS ANTITUMOR/ANTICANCER AGENTS AND TO TREAT A NUMBER OF CONDITIONS OR DISEASE STATES IN WHICH ANGIOGENESIS IS A FACTOR INCLUDING PSORIASIS, ACNE, ROSACEA, WARTS, ECZEMA, HEMANGIOMAS AND LYMPHANGIOGENESIS THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2002-10-08 — — US disclosed
EP-1242352-A2 CHALCONE AND ITS ANALOGS AS AGENTS FOR THE INHIBITION OF ANGIOGENESIS AND RELATED DISEASE STATES UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2002-09-25 — — EP disclosed
US-20020040029-A1 Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states BOWEN, J. PHILLIP 2002-04-04 — — US disclosed
WO-2001046110-A2 CHALCONE AND ITS ANALOGS AS AGENTS FOR THE INHIBITION OF ANGIOGENESIS AND RELATED DISEASE STATES THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2001-06-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150011488-A1 ANTIVIRAL EPICATECHINS, EPICATECHIN OLIGOMERS, OR THIOLATED EPICATECHINS FROM THEOBROMA CACAO FOR TREATMENT OF GENITAL WARTS CUTA, OGG1, HAAO MAOB 3198/4885MIF 1429/4885MEN1 2289/4885
US-20170035726-A1 ANTIVIRAL EPICATECHINS, EPICATECHIN OLIGOMERS, OR THIOLATED EPICATECHINS FROM THEOBROMA CACAO FOR TREATMENT OF GENITAL WARTS CUTA, OGG1, HAAO MAOB 3198/4885MIF 1429/4885MEN1 2289/4885
US-20020040029-A1 Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states FLT1, FLT4, VEGFA MAOB 2579/4885MIF 534/4885MEN1 3306/4885
US-20090018167-A1 Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states FLT1, FLT4, VEGFA MAOB 2526/4885MIF 332/4885MEN1 3400/4885
US-20030027830-A1 Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states FLT1, VEGFA, FLT4 MAOB 1509/4885MIF 220/4885MEN1 3069/4885
US-20110218241-A1 ANTIVIRAL EPICATECHINS, EPICATECHIN OLIGOMERS, OR THIOLATED EPICATECHINS FROM THEOBROMA CACAO FOR TREATMENT OF GENITAL WARTS CUTA, OGG1, MGMT MAOB 3080/4885MIF 1570/4885MEN1 2062/4885
US-20050148599-A1 Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states FLT1, VEGFA, FLT4 MAOB 1509/4885MIF 220/4885MEN1 3069/4885
US-20190142792-A1 ANTIVIRAL EPICATECHINS, EPICATECHIN OLIGOMERS, OR THIOLATED EPICATECHINS FROM THEOBROMA CACAO FOR TREATMENT OF GENITAL WARTS CUTA, OGG1, HAAO MAOB 3198/4885MIF 1429/4885MEN1 2289/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.