SCHEMBL25844001

SCHEMBL25844001

CC(C)c1ncc(NC2CCC(=O)NC2=O)o1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 20/20 0.54
CRBN Q96SW2 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25567180 0.84 DDB1 (0.53) DDB1CRBN
SCHEMBL24890984 0.79 CRBN (0.50) DDB1CRBN
SCHEMBL24890983 0.79 CRBN (0.50) DDB1CRBN
SCHEMBL24890981 0.79 CRBN (0.50) DDB1CRBN
SCHEMBL23798048 0.79 DDB1 (0.54) DDB1CRBN
SCHEMBL25091486 0.76 DDB1 (0.57) DDB1CRBN
SCHEMBL25091497 0.76 DDB1 (0.57) DDB1CRBN
SCHEMBL25091488 0.75 DDB1 (0.71) DDB1CRBN
SCHEMBL23798693 0.74 DDB1 (0.61) DDB1CRBN
SCHEMBL25091822 0.74 DDB1 (0.48) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11691972-B2 Compounds for targeted degradation of BRD9 C4 THERAPEUTICS, INC. (US) 2023-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11691972-B2 Compounds for targeted degradation of BRD9 BRD9, BRD1, BRWD1 DDB1 390/4885CRBN 188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.