Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.49 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24890984 | 1.00 | CRBN (0.50) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL24890981 | 1.00 | CRBN (0.50) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL21946261 | 0.84 | CRBN (0.53) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL23594036 | 0.81 | CRBN (0.50) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL25844001 | 0.79 | DDB1 (0.54) | CRBNDDB1 | |
| SCHEMBL25626935 | 0.77 | CRBN (0.53) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL25627049 | 0.77 | CRBN (0.53) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL25627051 | 0.75 | CRBN (0.57) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL23594198 | 0.75 | CRBN (0.57) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL24833739 | 0.74 | CRBN (0.62) | CRBNDDB1IKZF3BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287928-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK WITH DIMINISHED IMID ACTIVITY | NURIX THERAPEUTICS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |