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SCHEMBL25844128

SCHEMBL25844128

Cc1ccc2c(c1)C(C)(C)c1c3c(c4ccccc4c1-2)OC(c1ccc(N2CCOCC2)cc1)(c1ccc2c(c1)C(C)(C)c1ccc4ccccc4c1-2)C=C3

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ ALK Q9UM73 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ PIK3CA P42336 3/20 0.31
▸ PIK3CD O00329 2/20 0.31
▸ PIK3CB P42338 2/20 0.31
▸ PIK3CG P48736 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25844099 0.95 — —
SCHEMBL25604301 0.94 PDK2 (0.32) MEN1MAPTKMT2APIK3CAPIK3CD
SCHEMBL25844134 0.93 ALK (0.32) ALKMEN1LMNAMAPTKMT2A
SCHEMBL25844125 0.93 MAPT (0.33) ALKMEN1LMNAMAPTKMT2A
SCHEMBL25844124 0.93 ALK (0.34) ALKMEN1LMNAMAPTKMT2A
SCHEMBL25844115 0.93 ALK (0.33) ALKMEN1LMNAMAPTKMT2A
SCHEMBL25844130 0.92 MEN1 (0.33) ALKMEN1LMNAMAPTKMT2A
SCHEMBL25844147 0.92 ALK (0.36) ALKMEN1LMNAMAPTKMT2A
SCHEMBL25844116 0.91 PDK2 (0.34) ALKMEN1LMNAMAPTKMT2A
SCHEMBL25844138 0.90 MAPT (0.35) ALKMEN1LMNAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230227717-A1 PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND SPECTACLES HOYA LENS THAILAND LTD. (TH) 2023-07-20 — — US disclosed