SCHEMBL25844613

SCHEMBL25844613

Cc1ccc(-c2c(C(F)(F)F)cc(C)cc2C(F)(F)F)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 3/20 0.49
CYP11B1 P15538 1/20 0.42
CYP11B2 P19099 1/20 0.42
ALDH1A1 P00352 2/20 0.41
AKR1C3 P42330 1/20 0.41
AKR1C2 P52895 1/20 0.41
GLA P06280 1/20 0.41
GAA P10253 1/20 0.41
HPGD P15428 1/20 0.41
ATM Q13315 1/20 0.41
ENPP1 P22413 1/20 0.38
GABRP O00591 1/20 0.38
GABRD O14764 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRB1 P18505 1/20 0.38
GABRG2 P18507 1/20 0.38
GABRB3 P28472 1/20 0.38
GABRA5 P31644 1/20 0.38
GABRA3 P34903 1/20 0.38
GABRA2 P47869 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20108386 0.90 AR (0.45) ARCYP11B1CYP11B2ALDH1A1AKR1C3
SCHEMBL26373611 0.83 AR (0.42) ARCYP11B1CYP11B2ALDH1A1AKR1C3
SCHEMBL18272233 0.81 SMN1; SMN2 (0.40) ARALDH1A1GLAGAAFFAR4
SCHEMBL26373608 0.80 AR (0.41) ARCYP11B1CYP11B2ALDH1A1AKR1C3
SCHEMBL7702032 0.79 AR (0.46) ARCYP11B1CYP11B2ALDH1A1AKR1C3
SCHEMBL26373609 0.77 AR (0.39) ARCYP11B1CYP11B2ALDH1A1AKR1C3
SCHEMBL19323000 0.77 AKR1C3 (0.58) ARCYP11B1CYP11B2ALDH1A1AKR1C3
SCHEMBL20108617 0.75 CYP11B1 (0.38) ARCYP11B1CYP11B2ALDH1A1AKR1C3
SCHEMBL22304413 0.74 AKR1C3 (0.55) ARCYP11B1CYP11B2AKR1C3AKR1C2
SCHEMBL20108429 0.74 TSHR (0.38) AKR1C2GABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230220161-A1 POLYIMIDE PRECURSOR PREPARED BY USING POLYCYCLIC MONOMER INCLUDING TRIFLUOROMETHYL GROUP AND FLEXIBLE POLYIMIDE OBTAINED BY USING THE SAME KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2023-07-13 US disclosed