SCHEMBL25844826

SCHEMBL25844826

CC(C)(I)C(=O)Oc1cccc(C(=O)OC(CS(=O)(=O)O)C(F)(F)F)c1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.37
ESR2 Q92731 2/20 0.37
KDM4E B2RXH2 1/20 0.34
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
CASP3 P42574 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
DDR1 Q08345 2/20 0.33
SERPINE1 P05121 1/20 0.33
KAT6A Q92794 5/20 0.32
MAPK1 P28482 1/20 0.32
CETP P11597 1/20 0.32
HDAC8 Q9BY41 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25845026 0.90 ESR1 (0.38) ESR1ESR2KDM4EKMT2AMEN1
SCHEMBL26313010 0.88 ESR1 (0.36) ESR1ESR2KDM4EKMT2AMEN1
SCHEMBL26312797 0.85 ELANE (0.38) ESR1ESR2KDM4EKMT2AMEN1
SCHEMBL23426243 0.83 KAT6A (0.34) ESR1ESR2KDM4EKMT2AMEN1
SCHEMBL19755961 0.79 KAT6A (0.35) KMT2AMEN1KAT6AMAPK1
SCHEMBL18775853 0.78 PARP1 (0.40) KDM4EKMT2A
SCHEMBL18775881 0.78 KMT2A (0.44) ESR1ESR2KDM4EKMT2AMEN1
SCHEMBL25845200 0.78 ELANE (0.33)
SCHEMBL18775731 0.77 MAPK1 (0.40) KDM4EKMT2AMEN1DDR1MAPK1
SCHEMBL25527731 0.77 KMT2A (0.34) KDM4EKMT2AMEN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11709426-B2 Resist composition and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-07-25 US disclosed