SCHEMBL25844847

SCHEMBL25844847

O=C(/C=C/I)Oc1ccc(C(=O)OC(CS(=O)(=O)O)C(F)(F)F)cc1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
ACR P10323 2/20 0.30
PRSS1 P07477 1/20 0.30
MAOB P27338 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25845044 0.92 MEN1 (0.31) KMT2AMEN1POLBACRPRSS1
SCHEMBL25845200 0.84 ELANE (0.33) ACRPRSS1ALDH1A1MAPT
SCHEMBL18775684 0.84 MAPT (0.41) KMT2AMEN1POLBACRMAPT
SCHEMBL25845154 0.82 ELANE (0.37) ACRPRSS1ALDH1A1MAPT
SCHEMBL25844843 0.82 ELANE (0.31) ACRPRSS1
SCHEMBL18775779 0.81 CA1 (0.45) KMT2AMEN1POLBMAPT
SCHEMBL18775742 0.81 TRPV1 (0.36) KMT2AMEN1
SCHEMBL18775757 0.81 ALDH1A1 (0.30) ALDH1A1
SCHEMBL25844848 0.81
SCHEMBL20009240 0.80 PARP10 (0.44) KMT2AMEN1MAOBALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11709426-B2 Resist composition and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-07-25 US disclosed