SCHEMBL25845375

SCHEMBL25845375

CC1(C)c2ccccc2-c2cccc(-c3ccc4c5c(cccc35)-c3ccccc3S4)c21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
CHRM2 P08172 1/20 0.31
HTR1A P08908 1/20 0.31
ADRA2A P08913 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
CYP2D6 P10635 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD1 P21728 1/20 0.31
TBXA2R P21731 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
CYP2C19 P33261 1/20 0.31
ADRA1A P35348 1/20 0.31
OPRM1 P35372 1/20 0.31
DRD3 P35462 1/20 0.31
SLC6A3 Q01959 1/20 0.31
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25869575 0.85 PDK2 (0.34) CRHBPCRHR2KEAP1NFE2L2
SCHEMBL25869466 0.85 CRHBP (0.34) CRHBPCRHR2KEAP1NFE2L2
SCHEMBL16558474 0.84 CRHBP (0.39) CRHBPCRHR2KEAP1NFE2L2CHRM2
SCHEMBL25845578 0.84 CRHBP (0.30) CRHBPCRHR2KEAP1NFE2L2
SCHEMBL25845581 0.84 PDK2 (0.34) CRHBPCRHR2KEAP1NFE2L2
SCHEMBL25845372 0.83 PDK2 (0.32)
SCHEMBL16558472 0.83 CRHBP (0.41) CRHBPCRHR2KEAP1NFE2L2CHRM2
SCHEMBL25869339 0.82 PDK2 (0.34)
SCHEMBL25853921 0.82 KDM4E (0.35)
SCHEMBL25845583 0.81 TYMS (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023120714-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2023-06-29 WO disclosed