Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | POLB | P06746 | 3/20 | 0.70 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17264124 | 0.93 | ALDH1A1 (0.75) | ALDH1A1POLBHTTMAPTGAA | |
| SCHEMBL160768 | 0.83 | ALDH1A1 (1.00) | ALDH1A1POLBHTTMAPTGAA | |
| SCHEMBL30336487 | 0.83 | ALDH1A1 (1.00) | ALDH1A1POLBHTTMAPTGAA | |
| SCHEMBL25845549 | 0.83 | ALDH1A1 (0.55) | ALDH1A1POLBHTTMAPTGAA | |
| SCHEMBL12074538 | 0.81 | ALDH1A1 (0.73) | ALDH1A1POLBHTTMAPTGAA | |
| SCHEMBL76629 | 0.81 | ALDH1A1 (0.96) | ALDH1A1POLBHTTMAPTGAA | |
| SCHEMBL15358686 | 0.80 | ALDH1A1 (0.81) | ALDH1A1POLBHTTMAPTGAA | |
| SCHEMBL29990026 | 0.80 | ALDH1A1 (1.00) | ALDH1A1POLBHTTMAPTGAA | |
| SCHEMBL17450415 | 0.79 | ALDH1A1 (0.68) | ALDH1A1POLBHTTMAPTGAA | |
| SCHEMBL6819782 | 0.78 | ALDH1A1 (0.53) | ALDH1A1POLBHTTMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691972-B2 | Compounds for targeted degradation of BRD9 | C4 THERAPEUTICS, INC. (US) | 2023-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691972-B2 | Compounds for targeted degradation of BRD9 | BRD9, BRD1, BRWD1 | ALDH1A1 4230/4885POLB 2403/4885HTT 536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.