Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153470 | 0.93 | NAMPT (0.56) | NAMPTKMT2AMEN1LMNAHPGD | |
| SCHEMBL28241421 | 0.91 | PTPN1 (0.70) | KMT2AMEN1LMNAHPGDCYP2C9 | |
| SCHEMBL6154813 | 0.89 | KMT2A (0.54) | NAMPTKMT2AMEN1LMNAHPGD | |
| SCHEMBL6154809 | 0.89 | KMT2A (0.54) | NAMPTKMT2AMEN1LMNAHPGD | |
| SCHEMBL6153241 | 0.89 | SIRT2 (0.64) | NAMPTKMT2AMEN1LMNAHPGD | |
| SCHEMBL3093727 | 0.89 | CYP2C9 (0.61) | NAMPTKMT2AMEN1LMNAHPGD | |
| Hydrochloric Acid SCHEMBL6153392 | 0.87 | SIRT2 (0.62) | NAMPTKMT2AMEN1LMNAHPGD | |
| SCHEMBL6153820 | 0.84 | NAMPT (0.50) | NAMPTKMT2AMEN1LMNAHPGD | |
| SCHEMBL6153818 | 0.84 | MAPK14 (0.54) | NAMPTKMT2AMEN1LMNAHPGD | |
| SCHEMBL11731164 | 0.83 | KMT2A (0.66) | NAMPTKMT2AMEN1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122212-A2 | SUBSTITUTED PHENYL ETHYNYL PYRIDINE CARBOXAMIDES AS POTENT INHIBITORS OF SARS VIRUS | SOUTHERN RESEARCH INSTITUTE (US) | 2023-06-29 | — | — | WO | disclosed |