SCHEMBL25845751

SCHEMBL25845751

CC(C)(C)OC(=O)N1CCC(CCC2CCN(c3ccc(N)cc3)CC2)CC1

nearest known ligand 0.64

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 14/20 0.64
ALDH1A1 P00352 2/20 0.51
MAPT P10636 2/20 0.51
LMNA P02545 1/20 0.51
KDM4E B2RXH2 1/20 0.50
PKM P14618 1/20 0.50
TGFBR1 P36897 1/20 0.49
NPC1 O15118 1/20 0.48
MAPK1 P28482 1/20 0.48
HTT P42858 1/20 0.48
RAB9A P51151 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10036433 0.90 GPR119 (0.79) GPR119ALDH1A1MAPTLMNANPC1
SCHEMBL13757755 0.90 GPR119 (0.58) GPR119ALDH1A1MAPTLMNATGFBR1
SCHEMBL27035718 0.89 GPR119 (0.65) GPR119ALDH1A1MAPTLMNAKDM4E
SCHEMBL20046621 0.88 GPR119 (0.56) GPR119ALDH1A1MAPTLMNATGFBR1
SCHEMBL55667 0.85 MAPT (0.67) GPR119ALDH1A1MAPTLMNAHTT
Hydrochloric Acid SCHEMBL7371653 0.84 MAPT (0.65) GPR119ALDH1A1MAPTLMNAHTT
Hydrochloric Acid SCHEMBL4934215 0.84 MAPT (0.65) GPR119ALDH1A1MAPTLMNAHTT
SCHEMBL23783156 0.84 GPR119 (0.59) GPR119ALDH1A1MAPTLMNANPC1
SCHEMBL8352974 0.84 GPR119 (0.59) GPR119ALDH1A1MAPTLMNANPC1
SCHEMBL13313520 0.84 GPR119 (0.59) GPR119ALDH1A1MAPTLMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823124-A Compounds for targeted degradation of BRD9 C4医药公司 2025-04-15 CN disclosed
US-20250084081-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 THERAPEUTICS, INC. (US) 2025-03-13 US disclosed
CN-115279370-B Compounds for targeted degradation of BRD9 C4医药公司 2025-01-10 CN disclosed
US-12157735-B2 Compounds for targeted degradation of BRD9 C4 THERAPEUTICS, INC. (US) 2024-12-03 US disclosed
US-12049464-B2 Compounds for targeted degradation of BRD9 C4 THERAPEUTICS, INC. (US) 2024-07-30 US disclosed
US-20240051953-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 THERAPEUTICS, INC. (US) 2024-02-15 US disclosed
US-11691972-B2 Compounds for targeted degradation of BRD9 C4 THERAPEUTICS, INC. (US) 2023-07-04 US disclosed
US-11691972-B2 Compounds for targeted degradation of BRD9 C4 THERAPEUTICS, INC. (US) 2023-07-04 US disclosed
US-20230060334-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 THERAPEUTICS, INC. (US) 2023-03-02 US disclosed
EP-4114392-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 Therapeutics, Inc. (US) 2023-01-11 EP disclosed
CN-115279370-A Compounds for targeted degradation of BRD9 C4医药公司 2022-11-01 CN disclosed
US-20220098194-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 THERAPEUTICS, INC. (US) 2022-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230060334-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 BRD9, BRD1, BRWD1 GPR119 2909/4885ALDH1A1 4303/4885MAPT 1280/4885
US-20220098194-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 BRD9, BRD1, BRWD1 GPR119 2909/4885ALDH1A1 4303/4885MAPT 1280/4885
US-12157735-B2 Compounds for targeted degradation of BRD9 BRD9, BRD1, BRWD1 GPR119 2909/4885ALDH1A1 4303/4885MAPT 1280/4885
US-12049464-B2 Compounds for targeted degradation of BRD9 BRD9, BRD1, BRWD1 GPR119 2909/4885ALDH1A1 4303/4885MAPT 1280/4885
US-20240051953-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 BRD9, BRD1, BRWD1 GPR119 2909/4885ALDH1A1 4303/4885MAPT 1280/4885
US-20250084081-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 BRD9, BRD1, BRWD1 GPR119 2909/4885ALDH1A1 4303/4885MAPT 1280/4885
US-11691972-B2 Compounds for targeted degradation of BRD9 BRD9, BRD1, BRWD1 GPR119 3145/4885ALDH1A1 4230/4885MAPT 1277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.