SCHEMBL258461

SCHEMBL258461

CC(=O)Oc1cccc(C(=O)O)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.68
GAA P10253 2/20 0.68
CYP3A4 P08684 1/20 0.61
AKR1C3 P42330 1/20 0.61
HSD17B10 Q99714 2/20 0.58
KMT2A Q03164 2/20 0.57
MEN1 O00255 1/20 0.57
ELANE P08246 1/20 0.56
ACHE P22303 1/20 0.56
RAB9A P51151 3/20 0.55
ALDH1A1 P00352 2/20 0.55
NPC1 O15118 2/20 0.55
TP53 P04637 1/20 0.55
HTT P42858 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
KDM4E B2RXH2 2/20 0.55
TSHR P16473 1/20 0.55
MAPT P10636 2/20 0.54
MAPK1 P28482 1/20 0.54
TDP1 Q9NUW8 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29492631 1.00 LMNA (0.68) LMNAGAACYP3A4AKR1C3HSD17B10
SCHEMBL9360465 0.98 LMNA (0.66) LMNAGAACYP3A4AKR1C3HSD17B10
Hydrochloric Acid SCHEMBL9082486 0.98 LMNA (0.66) LMNAGAACYP3A4AKR1C3HSD17B10
Hydrazine SCHEMBL8166461 0.96 LMNA (0.64) LMNAGAACYP3A4AKR1C3HSD17B10
Propane SCHEMBL27935115 0.95 LMNA (0.62) LMNAGAACYP3A4AKR1C3HSD17B10
SCHEMBL9701119 0.89 AKR1C3 (0.63) LMNAGAACYP3A4AKR1C3HSD17B10
SCHEMBL10397747 0.88 AKR1C3 (0.72) LMNAGAAAKR1C3HSD17B10KMT2A
SCHEMBL5314324 0.87 ELANE (0.70) LMNAGAACYP3A4KMT2AMEN1
SCHEMBL3141164 0.86 LMNA (0.63) LMNAGAACYP3A4KMT2AMEN1
SCHEMBL30239922 0.86 LMNA (0.63) LMNAGAACYP3A4KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 506 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192256-A Substituted benzoic acid trifluoro-alkyl thio alkyl thioester derivative and preparation method and application thereof 浙江大学 2025-06-24 CN claimed
CN-114573453-B Selective of Carboxylic ester cleavage process 荆楚理工学院 2024-12-03 CN claimed
CN-114249651-A Organic rare earth complex microsphere, preparation method thereof and application of ammonia water 包头稀土研究院 2022-03-29 CN claimed
CN-113667281-A Low-dielectric-constant TLCP material and preparation method thereof 宁夏清研高分子新材料有限公司 2021-11-19 CN claimed
US-20180273819-A1 THERMAL ENERGY STORAGE PHASE AND TEMPERATURE STABILIZATION CHANGE MATERIALS COMPRISING TRIAMINES AND METHODS FOR MAKING AND USING THEM ENTROPY SOLUTIONS LLC (US) 2018-09-27 US claimed
US-9534138-B2 Polymer coating system for improved tribological performance ATSP Innovations (US) 2017-01-03 US claimed
WO-2016179028-A1 THERMAL ENERGY STORAGE PHASE AND TEMPERATURE STABILIZATION CHANGE MATERIALS AND METHODS FOR MAKING AND USING THEM ENTROPY SOLUTIONS, LLC. (US) 2016-11-10 WO claimed
US-20150284586-A1 Polymer Coating System For Improved Tribological Performance ATSP INNOVATIONS, LLC (US) 2015-10-08 US claimed
US-20130337183-A1 POLYMER COATING SYSTEM FOR IMPROVED TRIBOLOGICAL PERFORMANCE ATSP INNOVATIONS, LLC 2013-12-19 US claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
US-4748161-A Triterpenyl esters of organic acids and hypolipidemic agents composed of them AMANO PHARMACEUTICAL CO., LTD. (JP) 1988-05-31 US claimed
EP-0166542-A2 Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them AMANO PHARMACEUTICAL CO., LTD. (JP) 1986-01-02 EP claimed
JP-62250028-A None JP disclosed
JP-63277235-A None JP disclosed
EP-4598933-A1 PHOSPHORAMIDATE COMPOUNDS AND USES THEREOF Allorion Therapeutics Inc (US) 2025-08-13 EP disclosed
CN-120189404-A Use of substituted benzotrifluoride thioalkyl thioester derivatives for preventing and/or treating aging and alopecia 浙江大学 2025-06-24 CN disclosed
US-4161470-A Polyester of 6-hydroxy-2-naphthoic acid and para-hydroxy benzoic acid capable of readily undergoing melt processing CELANESE CORPORATION (US) 1979-07-17 US disclosed
US-4146702-A LIQUID CRYSTAL COPOLYESTERS PREPARED FROM AN AROMATIC DICARBOXYLIC ACID, A SUBSTITUTED HYDROQUINONE AND A M-ACYLOXYBENZOIC ACID EASTMAN KODAK COMPANY (US) 1979-03-27 US disclosed
EP-0001185-A1 Melt processable thermotropic wholly aromatic polyester comprising both para-oxybenzoyl and meta-oxybenzoyl moieties, moulding compounds, moulded articles and fibres based thereon CELANESE CORPORATION (US) 1979-03-21 EP disclosed
US-4130545-A Melt processable thermotropic wholly aromatic polyester comprising both para-oxybenzoyl and meta-oxybenzoyl moieties CELANESE CORPORATION (US) 1978-12-19 US disclosed