Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1266177 | 0.79 | RAD52 (0.46) | MAOBPKMTSHRKMT2ATHRB | |
| SCHEMBL1266178 | 0.79 | RAD52 (0.46) | MAOBPKMTSHRKMT2ATHRB | |
| SCHEMBL16378813 | 0.79 | ALDH1A1 (0.41) | MAOBPKMTSHRKMT2ATHRB | |
| SCHEMBL20205871 | 0.79 | KDM4E (0.41) | MAOBPKMTSHRKMT2ATHRB | |
| SCHEMBL19368247 | 0.79 | RAD52 (0.46) | MAOBPKMTSHRKMT2ATHRB | |
| SCHEMBL16378822 | 0.79 | ALDH1A1 (0.41) | MAOBPKMTSHRKMT2ATHRB | |
| SCHEMBL6653939 | 0.75 | MIF (0.40) | MAOBPKMTSHRKMT2AKDM4E | |
| SCHEMBL6656648 | 0.75 | MIF (0.40) | MAOBPKMTSHRKMT2AKDM4E | |
| SCHEMBL18924655 | 0.75 | MIF (0.40) | MAOBPKMTSHRKMT2AKDM4E | |
| SCHEMBL13130686 | 0.71 | MAPT (0.35) | MAOBPKMTSHRKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303312-B1 | PROCESS FOR PREPARING (E)-(5,6-DIHYDRO-1,4,2-DIOXAZINE-3-YL)(2-HYDROXYPHENYL)METHANONE O-METHYL OXIME | ARYSTA LIFESCIENCE CORP (JP) | 2023-07-19 | — | — | EP | disclosed |