Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 9/20 | 0.53 |
| ▸ | TACR2 | P21452 | 2/20 | 0.49 |
| ▸ | TACR1 | P25103 | 2/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | TEK | Q02763 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25233673 | 0.86 | GRM5 (0.56) | GRM5TACR2TACR1PDGFRBKDR | |
| SCHEMBL25286068 | 0.86 | MEN1 (0.57) | GRM5TACR2TACR1PDGFRBKDR | |
| SCHEMBL994977 | 0.86 | GRM5 (0.59) | GRM5TACR2TACR1KDR | |
| SCHEMBL25232354 | 0.85 | GRM5 (0.54) | GRM5TACR2TACR1PDGFRBKDR | |
| SCHEMBL25846553 | 0.84 | RXFP1 (0.51) | GRM5 | |
| SCHEMBL25274902 | 0.83 | TRPV1 (0.58) | GRM5TACR2TACR1KCNK9 | |
| SCHEMBL30563504 | 0.83 | NPC1 (0.54) | GRM5TACR2TACR1 | |
| SCHEMBL25246000 | 0.83 | NPC1 (0.54) | GRM5TACR2TACR1 | |
| SCHEMBL25233978 | 0.81 | GRM5 (0.55) | GRM5TACR2TACR1PDGFRBKDR | |
| SCHEMBL25237004 | 0.81 | NPC1 (0.57) | GRM5TACR2TACR1PDGFRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122212-A2 | SUBSTITUTED PHENYL ETHYNYL PYRIDINE CARBOXAMIDES AS POTENT INHIBITORS OF SARS VIRUS | SOUTHERN RESEARCH INSTITUTE (US) | 2023-06-29 | — | — | WO | disclosed |