Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.48 |
| ▸ | GRM5 | P41594 | 4/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25846457 | 0.84 | GRM5 (0.53) | GRM5 | |
| SCHEMBL25254448 | 0.79 | GRM5 (0.56) | GRM5RAB9AMAPTNPC1LMNA | |
| SCHEMBL30563419 | 0.79 | GRM5 (0.56) | GRM5RAB9AMAPTNPC1LMNA | |
| SCHEMBL25678186 | 0.79 | TP53 (0.57) | RXFP1MEN1KMT2ACASP3SENP8 | |
| SCHEMBL25276486 | 0.79 | AURKB (0.47) | RXFP1MEN1KMT2ACASP3SENP8 | |
| SCHEMBL25227508 | 0.79 | F10 (0.56) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL25229616 | 0.79 | TP53 (0.54) | RXFP1KMT2AGRM5THRBRAB9A | |
| SCHEMBL30563470 | 0.79 | F10 (0.56) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL25239345 | 0.78 | RAB9A (0.58) | MEN1KMT2AGRM5RAB9AMAPT | |
| SCHEMBL25676964 | 0.77 | AURKB (0.46) | RXFP1MEN1KMT2ACASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122212-A2 | SUBSTITUTED PHENYL ETHYNYL PYRIDINE CARBOXAMIDES AS POTENT INHIBITORS OF SARS VIRUS | SOUTHERN RESEARCH INSTITUTE (US) | 2023-06-29 | — | — | WO | disclosed |