Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.85 |
| ▸ | NOS1 | P29475 | 9/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5541270 | 1.00 | HSD17B10 (0.85) | HSD17B10NOS1AKR1B1KDM4EMEN1 | |
| SCHEMBL15144421 | 1.00 | HSD17B10 (0.85) | HSD17B10NOS1AKR1B1KDM4EMEN1 | |
| SCHEMBL13947293 | 1.00 | HSD17B10 (0.85) | HSD17B10NOS1AKR1B1KDM4EMEN1 | |
| SCHEMBL29776929 | 1.00 | HSD17B10 (0.85) | HSD17B10NOS1AKR1B1KDM4EMEN1 | |
| SCHEMBL29400382 | 1.00 | HSD17B10 (0.85) | HSD17B10NOS1AKR1B1KDM4EMEN1 | |
| SCHEMBL29776986 | 1.00 | HSD17B10 (0.85) | HSD17B10NOS1AKR1B1KDM4EMEN1 | |
| SCHEMBL30515237 | 0.89 | HSD17B10 (0.68) | HSD17B10AKR1B1 | |
| SCHEMBL25899101 | 0.85 | HSD17B10 (0.71) | HSD17B10NOS1AKR1B1KDM4EMEN1 | |
| SCHEMBL6363183 | 0.85 | HSD17B10 (0.71) | HSD17B10NOS1AKR1B1KDM4EMEN1 | |
| SCHEMBL13314521 | 0.84 | HSD17B10 (0.69) | HSD17B10NOS1AKR1B1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4358 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260048056-A1 | SOLID PHARMACEUTICAL COMPOSITIONS COMPRISING BIOPTERIN DERIVATIVES AND USES OF SUCH COMPOSITIONS | VASOPHARM GMBH (DE) | 2026-02-19 | — | — | US | claimed |
| US-20250288555-A1 | SYSTEMS AND METHODS TO IMPROVE EXERCISE TOLERANCE | EPICENTRX, INC. (US) | 2025-09-18 | — | — | US | claimed |
| CN-120142525-A | Method for detecting related substances in sapropterin hydrochloride tablet | 上海奥科达医药科技股份有限公司 | 2025-06-13 | — | — | CN | claimed |
| US-20250120977-A1 | METHODS OF TREATING PATIENTS SUFFERING FROM BRAIN INJURY AND METHODS OF INCREASING THE VALUE OF THE EXTENDED GLASGOW OUTCOME SCALE OF PATIENTS SUFFERING FROM BRAIN INJURY | VERINOS OPERATIONS GMBH (DE) | 2025-04-17 | — | — | US | claimed |
| EP-4537111-A2 | MULTI-OMICS ASSESSMENT | Prognomiq Inc (US) | 2025-04-16 | — | — | EP | claimed |
| CN-119816897-A | Multiple study assessment | 普罗科技有限公司 | 2025-04-11 | — | — | CN | claimed |
| WO-2025038846-A1 | L-ARGININE FORMULATIONS AND METHODS OF MANAGING PAIN | EMORY UNIVERSITY (US) | 2025-02-20 | — | — | WO | claimed |
| US-12171766-B2 | Methods of treating patients suffering from brain injury and methods of increasing the value of the extended Glasgow Outcome Scale of patients suffering from brain injury | VERINOS OPERATIONS GMBH (DE) | 2024-12-24 | — | — | US | claimed |
| WO-2024212361-A1 | USE OF BIOMARKER COMBINATION IN PREPARATION OF LUNG CANCER PREDICTION PRODUCT | 南京品生医学检验实验室有限公司 | 2024-10-17 | — | — | WO | claimed |
| WO-2024212363-A1 | USE OF BIOMARKER COMBINATION IN PREPARATION OF BREAST CANCER PREDICTION PRODUCT | 南京品生医学检验实验室有限公司 | 2024-10-17 | — | — | WO | claimed |
| EP-0689541-B1 | PTERIN DERIVATIVES AND THEIR USE FOR THE PREPARATION OF IMMUNOASSAYS | BRAHMS DIAGNOSTICA GMBH (DE) | 1996-10-09 | — | — | EP | claimed |
| EP-0689541-A1 | PTERIN DERIVATIVES AND THEIR USE FOR THE PREPARATION OF IMMUNOASSAYS | BRAHMS DIAGNOSTICA GMBH (DE) | 1996-01-03 | — | — | EP | claimed |
| WO-1994021636-A1 | PTERIN DERIVATIVES AND THEIR USE FOR THE PREPARATION OF IMMUNOASSAYS | B.R.A.H.M.S DIAGNOSTICA GMBH (DE) | 1994-09-29 | — | — | WO | claimed |
| EP-0191335-B1 | PREPARATION PROCESS OF (6R)-TETRAHYDRO-L-BIOPTERIN | SHIRATORI PHARMACEUTICAL CO. LTD. (JP) | 1991-08-14 | — | — | EP | claimed |
| US-4713454-A | CATALYTIC HYDROGENATION IN PRESENCE OF AMINE OF ERYTHROBIOPTERIN | SHIRATORI PHARMACEUTICAL CO., LTD. (JP) | 1987-12-15 | — | — | US | claimed |
| EP-0079574-B1 | PROCESS FOR PREPARING BIOPTERIN AND ITS DERIVATIVES | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-03-04 | — | — | EP | claimed |
| EP-0164964-A1 | Lipoidal biopterin compounds | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1985-12-18 | — | — | EP | claimed |
| US-4550109-A | PHENYLKETONURIA, PARKINSON'S DISEASE, DEPRESSION, SENILE DEMENTIA,ALZHEIMER'S DISEASE | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1985-10-29 | — | — | US | claimed |
| EP-0156330-A2 | Sulfate of 5,6,7,8-tetrahydro-l-erythro-biopterin and process for preparing the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-10-02 | — | — | EP | claimed |
| EP-0012444-B1 | DIAGNOSTIC METHOD, ESPECIALLY FOR THE EARLY RECOGNITION OF MALIGNANT TUMORS AND/OR VIRAL DISEASES, AND MEANS TO CARRY IT OUT | Wachter, Helmut, Univ.-Prof. Dr. (AT) | 1984-07-25 | — | — | EP | claimed |