SCHEMBL25899101

SCHEMBL25899101

CC(C)c1cnc2nc(N)[nH]c(=O)c2n1

nearest known ligand 0.71

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.71
NOS1 P29475 9/20 0.56
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 2/20 0.47
MEN1 O00255 1/20 0.47
MAPT P10636 1/20 0.47
THRB P10828 1/20 0.47
HPGD P15428 1/20 0.47
KMT2A Q03164 1/20 0.47
AKR1B1 P15121 3/20 0.46
LMNA P02545 1/20 0.44
GLA P06280 1/20 0.44
PMP22 Q01453 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29776986 0.85 HSD17B10 (0.85) HSD17B10NOS1KDM4EALDH1A1MEN1
SCHEMBL5541270 0.85 HSD17B10 (0.85) HSD17B10NOS1KDM4EALDH1A1MEN1
SCHEMBL258468 0.85 HSD17B10 (0.85) HSD17B10NOS1KDM4EALDH1A1MEN1
SCHEMBL29400382 0.85 HSD17B10 (0.85) HSD17B10NOS1KDM4EALDH1A1MEN1
SCHEMBL13947293 0.85 HSD17B10 (0.85) HSD17B10NOS1KDM4EALDH1A1MEN1
SCHEMBL29776929 0.85 HSD17B10 (0.85) HSD17B10NOS1KDM4EALDH1A1MEN1
SCHEMBL15144421 0.85 HSD17B10 (0.85) HSD17B10NOS1KDM4EALDH1A1MEN1
SCHEMBL24811788 0.82 NOS1 (0.60) HSD17B10NOS1KDM4EALDH1A1MEN1
SCHEMBL24574329 0.81 HSD17B10 (0.67) HSD17B10NOS1KDM4EALDH1A1MEN1
SCHEMBL23028910 0.81 HSD17B10 (0.67) HSD17B10NOS1KDM4EALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230279426-A1 MODIFIED VIRAL COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-09-07 US disclosed
US-20230279426-A1 MODIFIED VIRAL COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-09-07 US disclosed
US-20230226214-A1 BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-07-20 US disclosed
US-20230226214-A1 BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226214-A1 BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION HAVCR2, FCGR3B, FCGR2A HSD17B10 4659/4885NOS1 4318/4885KDM4E 4323/4885
US-20230279426-A1 MODIFIED VIRAL COMPOSITIONS FOR VIRAL TRANSDUCTION HAVCR2, ASGR1, FCGR3B HSD17B10 4755/4885NOS1 4179/4885KDM4E 3970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.