Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25832827 | 0.79 | CYP19A1 (0.39) | ESRRG | |
| SCHEMBL25820285 | 0.79 | CYP19A1 (0.37) | ESRRGPIM1PIM3PIM2BRAF | |
| SCHEMBL19756414 | 0.68 | PPARA (0.39) | PRMT5WDR77 | |
| SCHEMBL19756413 | 0.67 | SMN1; SMN2 (0.50) | PRMT5WDR77 | |
| SCHEMBL21282892 | 0.66 | MKNK1 (0.50) | PIM1PIM3PIM2PRMT5WDR77 | |
| SCHEMBL13086421 | 0.65 | CYP2D6 (0.38) | PIM1PIM3PIM2PRMT5WDR77 | |
| SCHEMBL19756421 | 0.64 | PRMT5 (0.40) | PRMT5WDR77 | |
| SCHEMBL725480 | 0.64 | PRMT5 (0.34) | PRMT5WDR77 | |
| SCHEMBL13086621 | 0.64 | MKNK1 (0.49) | PRMT5WDR77 | |
| SCHEMBL13086628 | 0.63 | CYP2A6 (0.51) | PIM1PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | ESRRG 604/4885PIM1 1187/4885PIM3 322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.