SCHEMBL25847351

SCHEMBL25847351

Cc1ccnc2c1ccc1ccc(-c3cccc(-c4ccccc4)c3)nc12

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 0.54
CCR8 P51685 3/20 0.54
CCR5 P51681 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
PSMD14 O00487 1/20 0.41
COPS5 Q92905 1/20 0.41
KMO O15229 2/20 0.37
CAMK2D Q13557 1/20 0.36
PARP1 P09874 1/20 0.36
WNT3A P56704 1/20 0.36
MAP4K4 O95819 1/20 0.35
AR P10275 1/20 0.35
ROCK1 Q13464 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21032004 0.90 CCR1 (0.58) CCR1CCR8CCR5L3MBTL1PSMD14
SCHEMBL21031996 0.90 CCR1 (0.61) CCR1CCR8CCR5L3MBTL1PSMD14
SCHEMBL29340593 0.86 CCR1 (0.49) CCR1CCR8CCR5L3MBTL1PSMD14
SCHEMBL29340596 0.86 CCR1 (0.49) CCR1CCR8CCR5L3MBTL1PSMD14
SCHEMBL21031252 0.85 CCR1 (0.57) CCR1CCR8CCR5L3MBTL1PSMD14
SCHEMBL21031998 0.84 CCR1 (0.59) CCR1CCR8CCR5L3MBTL1PSMD14
SCHEMBL29340592 0.84 CCR1 (0.49) CCR1CCR8CCR5L3MBTL1PSMD14
SCHEMBL29340597 0.84 CCR1 (0.49) CCR1CCR8CCR5L3MBTL1PSMD14
SCHEMBL29340595 0.81 CCR1 (0.51) CCR1CCR8CCR5L3MBTL1PSMD14
SCHEMBL25850758 0.81 PARP1 (0.49) KMOPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes KCNQ2, KCNQ1, KCNQ4 CCR1 4431/4885CCR8 4738/4885CCR5 2749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.