Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.61 |
| ▸ | CCR8 | P51685 | 3/20 | 0.61 |
| ▸ | CCR5 | P51681 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.42 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21032004 | 0.97 | CCR1 (0.58) | CCR1CCR8CCR5L3MBTL1PSMD14 | |
| SCHEMBL25847351 | 0.90 | CCR1 (0.54) | CCR1CCR8CCR5L3MBTL1PSMD14 | |
| SCHEMBL30439568 | 0.83 | TOP1 (0.44) | CCR1CCR8CCR5L3MBTL1ADORA2A | |
| SCHEMBL6328028 | 0.83 | TOP1 (0.44) | CCR1CCR8CCR5L3MBTL1ADORA2A | |
| SCHEMBL29340587 | 0.82 | CCR1 (0.53) | CCR1CCR8CCR5L3MBTL1PSMD14 | |
| SCHEMBL29340588 | 0.82 | CCR1 (0.53) | CCR1CCR8CCR5L3MBTL1PSMD14 | |
| SCHEMBL29340589 | 0.82 | CCR1 (0.53) | CCR1CCR8CCR5L3MBTL1PSMD14 | |
| SCHEMBL21032002 | 0.82 | CCR1 (0.64) | CCR1CCR8CCR5L3MBTL1PSMD14 | |
| SCHEMBL23517029 | 0.81 | HSP90AA1 (0.41) | CCR1CCR8CCR5L3MBTL1ADORA2A | |
| SCHEMBL16678847 | 0.81 | ALDH1A1 (0.49) | L3MBTL1ADORA2APARP1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691983-B2 | Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes | IDEMITSU KOSAN CO., LTD. (JP) | 2023-07-04 | — | — | US | disclosed |
| US-11691983-B2 | Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes | IDEMITSU KOSAN CO., LTD. (JP) | 2023-07-04 | — | — | US | disclosed |
| US-20190161497-A1 | SPECIFICALLY SUBSTITUTED BENZOFURO- AND BENZOTHIENOQUINOLINES FOR ORGANIC LIGHT EMITTING DIODES | IDEMITSU KOSAN CO., LTD. (JP) | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691983-B2 | Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes | KCNQ2, KCNQ1, KCNQ4 | CCR1 4431/4885CCR8 4738/4885CCR5 2749/4885 |
| US-20190161497-A1 | SPECIFICALLY SUBSTITUTED BENZOFURO- AND BENZOTHIENOQUINOLINES FOR ORGANIC LIGHT EMITTING DIODES | KCNQ2, KCNQ1, KCNQ4 | CCR1 4431/4885CCR8 4738/4885CCR5 2749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.