SCHEMBL25847353

SCHEMBL25847353

Cc1cnc2c(ccc3ccc(-c4cccc(-c5ccccc5)c4)nc32)c1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 0.54
CCR5 P51681 2/20 0.54
CCR8 P51685 2/20 0.54
KDM4E B2RXH2 2/20 0.45
PSMD14 O00487 1/20 0.45
COPS5 Q92905 1/20 0.45
SLC40A1 Q9NP59 1/20 0.41
PARP1 P09874 2/20 0.40
NFKBIA P25963 1/20 0.40
CYP1A2 P05177 1/20 0.39
KMO O15229 1/20 0.39
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
MAP4K4 O95819 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21032339 0.91 CCR1 (0.58) CCR1CCR5CCR8KDM4EPSMD14
SCHEMBL25847349 0.91 CCR1 (0.61) CCR1CCR5CCR8KDM4EPSMD14
SCHEMBL17899321 0.87 KDM4E (0.54) KDM4EPARP1KMOCYP11B1CYP11B2
SCHEMBL17899317 0.85 KDM4E (0.53) KDM4EPARP1CYP11B1CYP11B2
SCHEMBL18806866 0.85 KDM4E (0.55) KDM4EPARP1CYP11B1CYP11B2MAP4K4
SCHEMBL29314796 0.84 KDM4E (0.51) KDM4EPARP1CYP11B1CYP11B2
SCHEMBL29314792 0.84 KDM4E (0.51) KDM4EPARP1CYP11B1CYP11B2
SCHEMBL26364628 0.84 KDM4E (0.50) KDM4EPARP1CYP11B1CYP11B2MAP4K4
SCHEMBL25850758 0.83 PARP1 (0.49) PARP1KMOCYP11B1CYP11B2
SCHEMBL25850634 0.82 KDM4E (0.51) KDM4EPARP1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 US disclosed
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes KCNQ2, KCNQ1, KCNQ4 CCR1 4431/4885CCR5 2749/4885CCR8 4738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.