SCHEMBL25847434

SCHEMBL25847434

c1ccc2c(c1)ccc1c3cc(-c4nc(-c5ccc6ccc7oc8ccccc8c7c6c5)nc(-c5cccc6oc7ccccc7c56)n4)ccc3ccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
MAPT P10636 4/20 0.37
KDM4E B2RXH2 3/20 0.37
HPGD P15428 3/20 0.37
HSD17B10 Q99714 3/20 0.37
ALDH1A1 P00352 3/20 0.37
TSHR P16473 2/20 0.37
ALOX15 P16050 1/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37
GLA P06280 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 3/20 0.35
HPRT1 P00492 1/20 0.35
MAPK1 P28482 1/20 0.35
MEN1 O00255 2/20 0.35
ESR1 P03372 1/20 0.35
POLB P06746 1/20 0.35
HNF4A P41235 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25501238 0.97 TDP1 (0.38) TDP1L3MBTL1MAPTKDM4EHPGD
SCHEMBL24930664 0.96 TDP1 (0.42) TDP1L3MBTL1MAPTKDM4EHPGD
SCHEMBL25501428 0.95 L3MBTL1 (0.40) TDP1L3MBTL1MAPTKDM4EHPGD
SCHEMBL25502914 0.94 MAPT (0.36) TDP1L3MBTL1MAPTKDM4EHPGD
SCHEMBL25503176 0.94 TDP1 (0.42) TDP1L3MBTL1MAPTKDM4EHPGD
SCHEMBL25501590 0.94 HPGD (0.37) TDP1L3MBTL1MAPTKDM4EHPGD
SCHEMBL26375039 0.94 TDP1 (0.40) TDP1L3MBTL1MAPTKDM4EHPGD
SCHEMBL25660726 0.94 TDP1 (0.40) TDP1L3MBTL1MAPTKDM4EHPGD
SCHEMBL23822735 0.94 L3MBTL1 (0.41) TDP1L3MBTL1MAPTKDM4EHPGD
SCHEMBL23820650 0.94 L3MBTL1 (0.41) TDP1L3MBTL1MAPTKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023132694-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-07-13 WO disclosed