Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.60 |
| ▸ | KIT | P10721 | 9/20 | 0.57 |
| ▸ | ABL1 | P00519 | 8/20 | 0.57 |
| ▸ | BCR | P11274 | 4/20 | 0.57 |
| ▸ | LCK | P06239 | 6/20 | 0.56 |
| ▸ | CSF1R | P07333 | 6/20 | 0.56 |
| ▸ | ABL2 | P42684 | 5/20 | 0.56 |
| ▸ | BRAF | P15056 | 4/20 | 0.56 |
| ▸ | EGFR | P00533 | 3/20 | 0.56 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.56 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.56 |
| ▸ | FYN | P06241 | 2/20 | 0.56 |
| ▸ | LYN | P07948 | 2/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.56 |
| ▸ | FGR | P09769 | 2/20 | 0.56 |
| ▸ | SRC | P12931 | 2/20 | 0.56 |
| ▸ | NQO2 | P16083 | 2/20 | 0.56 |
| ▸ | EPHA8 | P29322 | 2/20 | 0.56 |
| ▸ | FRK | P42685 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL724511 | 0.90 | BTK (0.60) | BTKKITABL1BCRLCK | |
| SCHEMBL31436906 | 0.89 | BTK (0.62) | BTKKITABL1BCRLCK | |
| SCHEMBL8214408 | 0.85 | BTK (0.59) | BTKKITABL1BCRLCK | |
| SCHEMBL15381992 | 0.85 | BTK (0.69) | BTKKITABL1BCRLCK | |
| SCHEMBL4006161 | 0.84 | BTK (0.63) | BTKKITABL1BCRLCK | |
| SCHEMBL846560 | 0.84 | BTK (0.65) | BTKKITABL1BCRLCK | |
| SCHEMBL31436860 | 0.84 | BTK (0.65) | BTKKITABL1BCRLCK | |
| SCHEMBL3557025 | 0.83 | BRAF (0.74) | KITCSF1RBRAFEGFR | |
| SCHEMBL19646438 | 0.83 | BTK (0.57) | BTKKITABL1BCRLCK | |
| SCHEMBL3709638 | 0.82 | BTK (0.63) | BTKKITABL1BCRLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250092032-A1 | DEOXYCYTIDINE KINASE INHIBITORS | INSTITUT JEAN PAOLI & IRENE CALMETTES CENTRE REGIONAL DE LUTTE CONTRE LE CANCER (FR) | 2025-03-20 | — | — | US | disclosed |
| WO-2023135330-A1 | DEOXYCYTIDINE KINASE INHIBITORS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-07-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250092032-A1 | DEOXYCYTIDINE KINASE INHIBITORS | DCK, DTYMK, TYMP | BTK 559/4885KIT 509/4885ABL1 147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.