Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770827 | 0.81 | TSHR (0.36) | HTTTSHRMAPTHPGDSMN1; SMN2 | |
| SCHEMBL7770832 | 0.81 | MAPT (0.37) | HTTTSHRMAPTHPGDSMN1; SMN2 | |
| SCHEMBL5861571 | 0.80 | KDM4C (0.42) | KDM4CMAPTCTSK | |
| SCHEMBL7808415 | 0.79 | TSHR (0.42) | HTTTSHRMAPTHCAR2HPGD | |
| SCHEMBL753141 | 0.77 | KDM4C (0.43) | KDM4CTSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL76832 | 0.73 | KDM4C (0.41) | KDM4CCTSKGAA | |
| SCHEMBL20907637 | 0.72 | TSHR (0.36) | HTTTSHRMAPTHPGDSMN1; SMN2 | |
| SCHEMBL20908067 | 0.72 | ALDH1A1 (0.36) | HTTTSHRMAPTHPGDSMN1; SMN2 | |
| SCHEMBL19509436 | 0.72 | MAPT (0.37) | HTTTSHRMAPTHPGDSMN1; SMN2 | |
| SCHEMBL21834933 | 0.71 | KDM4C (0.39) | KDM4CCTSKGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215512-A1 | DEUTERATED 1-PIPERAZINO-3-PHENYL INDANES FOR TREATMENT OF SCHIZOPHRENIA | H. Lundbeck A/S (DK) | 2023-07-26 | — | — | EP | disclosed |