Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.38 |
| ▸ | CHRNG | P07510 | 2/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.38 |
| ▸ | CHRND | Q07001 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16485195 | 0.91 | AKT1 (0.49) | AKT1OPRK1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL20041101 | 0.88 | AKT1 (0.45) | AKT1OPRK1OPRD1OPRM1 | |
| SCHEMBL24581817 | 0.88 | AKT1 (0.44) | AKT1OPRK1CTSB | |
| SCHEMBL26082961 | 0.88 | AKT1 (0.48) | AKT1OPRK1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL20646327 | 0.87 | AKT1 (0.45) | AKT1OPRK1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL27336666 | 0.86 | AKT1 (0.45) | AKT1OPRK1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL25871146 | 0.85 | AKT1 (0.45) | AKT1OPRK1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL27336140 | 0.84 | AKT1 (0.42) | AKT1OPRK1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL27336098 | 0.84 | AKT1 (0.42) | AKT1OPRK1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL25871508 | 0.83 | AKT1 (0.47) | AKT1MMP1MMP3MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212552-A1 | ANTI-HER2 ANTIBODY-DRUG CONJUGATE | Daiichi Sankyo Company, Limited (JP) | 2023-07-19 | — | — | EP | disclosed |