Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | CPA2 | P48052 | 1/20 | 0.35 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24581817 | 0.93 | AKT1 (0.44) | AKT1OPRK1 | |
| SCHEMBL16485195 | 0.91 | AKT1 (0.49) | AKT1ALDH1A1OPRK1OPRD1OPRM1 | |
| SCHEMBL25848726 | 0.88 | AKT1 (0.49) | AKT1OPRK1OPRD1OPRM1 | |
| SCHEMBL26082961 | 0.87 | AKT1 (0.48) | AKT1OPRK1OPRD1OPRM1HRH1 | |
| SCHEMBL20646327 | 0.87 | AKT1 (0.45) | AKT1OPRK1OPRD1OPRM1 | |
| SCHEMBL21153677 | 0.86 | ALDH1A1 (0.42) | ALDH1A1OPRK1POLBOPRD1OPRM1 | |
| SCHEMBL27336666 | 0.86 | AKT1 (0.45) | AKT1OPRK1OPRD1OPRM1HRH1 | |
| SCHEMBL30805368 | 0.85 | AKT1 (0.43) | AKT1HRH1 | |
| SCHEMBL26129741 | 0.85 | AKT1 (0.45) | AKT1 | |
| SCHEMBL31310248 | 0.85 | AKT1 (0.45) | AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2907824-B1 | ANTIBODY-DRUG CONJUGATE | DAIICHI SANKYO CO LTD (JP) | 2018-04-11 | — | — | EP | disclosed |