SCHEMBL25849160

SCHEMBL25849160

CC1(C)c2ccccc2-c2cccc(-c3cccc4c3C(c3ccccc3)(c3ccccc3)c3ccccc3O4)c21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
LMNA P02545 2/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
OPRK1 P41145 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SETD7 Q8WTS6 1/20 0.32
CFTR P13569 1/20 0.32
GOPC Q9HD26 1/20 0.32
DRD1 P21728 1/20 0.31
PGR P06401 1/20 0.31
KIF11 P52732 1/20 0.31
NPSR1 Q6W5P4 2/20 0.30
MAPK1 P28482 1/20 0.30
ATM Q13315 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25848908 0.88 KDM4E (0.37) KDM4ELMNAMEN1MAPTOPRK1
SCHEMBL22707433 0.88
SCHEMBL23028839 0.87 LMNA (0.31) KDM4ELMNAMEN1MAPTOPRK1
SCHEMBL25849157 0.86 MAPT (0.35) KDM4ELMNAMEN1MAPTOPRK1
SCHEMBL25865774 0.84 KDM4E (0.41) KDM4ELMNAMEN1MAPTOPRK1
SCHEMBL25849632 0.84 DRD1 (0.33) KDM4ELMNAMEN1MAPTOPRK1
SCHEMBL23028838 0.80 LMNA (0.39) KDM4ELMNAMEN1MAPTOPRK1
SCHEMBL25849778 0.79 KDM4E (0.37) KDM4ELMNAMEN1MAPTOPRK1
SCHEMBL25864352 0.79 KDM4E (0.37) KDM4ELMNAMEN1MAPTOPRK1
SCHEMBL25866769 0.79 MEN1 (0.44) KDM4ELMNAMEN1MAPTOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023120714-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2023-06-29 WO disclosed