SCHEMBL25849486 — predicted protein targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	KDM4E	B2RXH2	1/20	0.34

▸	ALDH1A1	P00352	1/20	0.34

▸	LMNA	P02545	1/20	0.34

▸	CYP1A2	P05177	2/20	0.33

▸	CYP3A4	P08684	2/20	0.33

▸	CYP2C9	P11712	2/20	0.33

▸	CYP2C19	P33261	2/20	0.33

▸	CYP2D6	P10635	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7894189	0.74	CYP11B1 (0.40)	KDM4EALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL17875680	0.73	EGFR (0.46)	KDM4EALDH1A1LMNACYP1A2CYP3A4
SCHEMBL27191761	0.69	RPS6KA5 (0.40)	KDM4EALDH1A1LMNA
SCHEMBL26923166	0.67	CYP1A2 (0.37)	KDM4EALDH1A1LMNACYP1A2CYP3A4
SCHEMBL24944742	0.67	KDM4E (0.34)	KDM4EALDH1A1
SCHEMBL25849490	0.67	GRM2 (0.38)	KDM4ELMNA
SCHEMBL34471790	0.66	KDM4E (0.35)	KDM4EALDH1A1LMNACYP1A2CYP3A4
SCHEMBL25105335	0.65	NQO2 (0.41)	KDM4EALDH1A1LMNACYP1A2CYP3A4
SCHEMBL23487171	0.65	HSD17B10 (0.37)	CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL31509717	0.65	HSD17B10 (0.44)	KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023132369-A1	NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING NRF2 ACTIVATION EFFECT	中外製薬株式会社	2023-07-13	—	—	WO	disclosed