Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 6/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24375535 | 0.78 | SLC9A1 (0.36) | SLC9A1KEAP1KDM4ELMNATSHR | |
| SCHEMBL24499231 | 0.76 | SLC9A1 (0.35) | SLC9A1KEAP1KDM4ELMNATSHR | |
| SCHEMBL21888877 | 0.73 | KDM4E (0.34) | SLC9A1KEAP1KDM4ELMNATSHR | |
| SCHEMBL30929215 | 0.72 | GRM2 (0.62) | GRM2SLC9A1KEAP1 | |
| SCHEMBL19911637 | 0.72 | GRM2 (0.62) | GRM2SLC9A1KEAP1 | |
| SCHEMBL22425913 | 0.71 | GRM2 (0.37) | GRM2SLC9A1KEAP1KDM4ELMNA | |
| SCHEMBL24944742 | 0.68 | KDM4E (0.34) | KDM4ETSHR | |
| SCHEMBL22425950 | 0.67 | GRM2 (0.37) | GRM2SLC9A1KEAP1 | |
| SCHEMBL29442714 | 0.67 | KEAP1 (0.38) | GRM2SLC9A1KEAP1KDM4ELMNA | |
| SCHEMBL31509642 | 0.67 | ADORA2A (0.39) | KDM4ELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023132369-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING NRF2 ACTIVATION EFFECT | 中外製薬株式会社 | 2023-07-13 | — | — | WO | disclosed |