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SCHEMBL25849554

SCHEMBL25849554

CC(C)c1cccc(C(C)C)c1N1/C(=C/C=C2C(=O)c3cc4ccccc4cc3C2=O)N(C)c2nc3ccccc3nc21

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 4/20 0.36
▸ NR1H2 P55055 1/20 0.36
▸ NR1H3 Q13133 1/20 0.36
▸ ANPEP P15144 4/20 0.35
▸ ILF3 Q12906 1/20 0.31
▸ BCL2 P10415 1/20 0.30
▸ MCL1 Q07820 1/20 0.30
▸ BCL2A1 Q16548 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ APEX1 P27695 1/20 0.30
▸ KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849586 0.94 DPP4 (0.41) DPP4NR1H2NR1H3ANPEPMEN1
SCHEMBL23337591 0.94 DPP4 (0.39) DPP4NR1H2NR1H3ANPEPILF3
SCHEMBL25849597 0.93 DPP4 (0.34) DPP4NR1H2NR1H3ANPEPMAPT
SCHEMBL25849592 0.92 DPP4 (0.34) DPP4NR1H2NR1H3ANPEP
SCHEMBL25849589 0.92 DPP4 (0.34) DPP4NR1H2NR1H3ANPEP
SCHEMBL25849598 0.91 TP53 (0.41) DPP4NR1H2NR1H3ANPEPMCL1
SCHEMBL25849595 0.90 USP8 (0.34) DPP4NR1H2NR1H3ANPEPMEN1
SCHEMBL25850277 0.89 ANPEP (0.37) DPP4NR1H2NR1H3ANPEP
SCHEMBL25849600 0.88 DPP4 (0.36) DPP4NR1H2NR1H3ANPEP
SCHEMBL23337888 0.86 DPP4 (0.37) DPP4NR1H2NR1H3ANPEPMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 — — US disclosed