SCHEMBL25849586

SCHEMBL25849586

CC(C)c1cccc(C(C)C)c1N1/C(=C/C=C2C(=O)c3ccccc3C2=O)N(C)c2nc3ccccc3nc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 5/20 0.41
NR1H2 P55055 1/20 0.41
NR1H3 Q13133 1/20 0.41
ANPEP P15144 5/20 0.38
HIF1A Q16665 1/20 0.35
MAPT P10636 4/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
APEX1 P27695 1/20 0.32
ALDH1A1 P00352 3/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
NPC1 O15118 1/20 0.32
AHR P35869 1/20 0.32
RAB9A P51151 1/20 0.32
CASP3 P42574 2/20 0.32
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849554 0.94 DPP4 (0.36) DPP4NR1H2NR1H3ANPEPMAPT
SCHEMBL25849583 0.89 DPP4 (0.34) DPP4NR1H2NR1H3ANPEPKMT2A
SCHEMBL25849597 0.87 DPP4 (0.34) DPP4NR1H2NR1H3ANPEPMAPT
SCHEMBL23337591 0.86 DPP4 (0.39) DPP4NR1H2NR1H3ANPEPMAPT
SCHEMBL25849580 0.86 DPP4 (0.36) DPP4NR1H2NR1H3ANPEP
SCHEMBL25849589 0.86 DPP4 (0.34) DPP4NR1H2NR1H3ANPEP
SCHEMBL25849592 0.86 DPP4 (0.34) DPP4NR1H2NR1H3ANPEP
SCHEMBL23337546 0.85 DPP4 (0.42) DPP4NR1H2NR1H3ANPEPMAPT
SCHEMBL25849598 0.85 TP53 (0.41) DPP4NR1H2NR1H3ANPEPMAPT
SCHEMBL26300124 0.84 DPP4 (0.39) DPP4NR1H2NR1H3ANPEPMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed