Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.48 |
| ▸ | DNMT3A | Q9Y6K1 | 3/20 | 0.48 |
| ▸ | CDK8 | P49336 | 2/20 | 0.47 |
| ▸ | CCNC | P24863 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.44 |
| ▸ | MET | P08581 | 2/20 | 0.43 |
| ▸ | GAK | O14976 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | CD38 | P28907 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24006240 | 0.94 | USP2 (0.58) | USP2MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL24003846 | 0.91 | MAPT (0.60) | USP2MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL30290896 | 0.90 | USP2 (0.53) | USP2MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL24010936 | 0.90 | USP2 (0.53) | USP2MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL24010240 | 0.88 | DNMT1 (0.58) | USP2MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL30290933 | 0.88 | DNMT1 (0.58) | USP2MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL23999380 | 0.86 | USP2 (0.61) | USP2MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL24006004 | 0.84 | USP2 (0.57) | USP2MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL25820661 | 0.84 | DNMT1 (0.53) | USP2MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL24003847 | 0.84 | DNMT1 (0.61) | USP2MAPTKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | USP2 4143/4885MAPT 3976/4885KMT2A 4131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.