SCHEMBL25849737

SCHEMBL25849737

CCCCCCN[C@@H](CC)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 2/20 0.51
EPHX1 P07099 8/20 0.47
GPR84 Q9NQS5 3/20 0.44
FFAR1 O14842 1/20 0.44
FNTA P49354 1/20 0.44
FNTB P49356 1/20 0.44
PLA2G2A P14555 2/20 0.42
PLA2G5 P39877 2/20 0.42
MAPT P10636 1/20 0.42
CASP2 P42575 1/20 0.42
LCK P06239 1/20 0.42
PPARD Q03181 1/20 0.42
ZDHHC20 Q5W0Z9 1/20 0.42
ZDHHC2 Q9UIJ5 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25305503 1.00 NOD1 (0.51) NOD1EPHX1GPR84FFAR1FNTA
SCHEMBL11423050 1.00 NOD1 (0.51) NOD1EPHX1GPR84FFAR1FNTA
SCHEMBL19750215 1.00 NOD1 (0.51) NOD1EPHX1GPR84FFAR1FNTA
SCHEMBL25244993 1.00 NOD1 (0.51) NOD1EPHX1GPR84FFAR1FNTA
SCHEMBL7081523 1.00 NOD1 (0.51) NOD1EPHX1GPR84FFAR1FNTA
SCHEMBL5309803 0.98 NOD1 (0.49) NOD1EPHX1GPR84FFAR1FNTA
SCHEMBL24660133 0.86 NOD1 (0.50) NOD1EPHX1GPR84FFAR1FNTA
SCHEMBL7568502 0.86 NOD1 (0.61) NOD1EPHX1GPR84FFAR1FNTA
SCHEMBL25253112 0.86 NOD1 (0.50) NOD1EPHX1GPR84FFAR1FNTA
SCHEMBL17080400 0.86 NOD1 (0.61) NOD1EPHX1GPR84FFAR1FNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118632867-A GLP-1/GIP receptor co-agonist prodrugs and uses thereof 诺和诺德股份有限公司 2024-09-10 CN claimed
EP-4466069-A1 GLP-1/GIP RECEPTOR CO-AGONIST PRODRUGS AND USES THEREOF Novo Nordisk A/S (DK) 2024-11-27 EP disclosed
CN-118632867-A GLP-1/GIP receptor co-agonist prodrugs and uses thereof 诺和诺德股份有限公司 2024-09-10 CN disclosed
US-20240083965-A1 PRODRUGS AND USES THEREOF NOVO NORDISK AS (DK) 2024-03-14 US disclosed
US-11840560-B2 Prodrugs and uses thereof NOVO NORDISK A/S (DK) 2023-12-12 US disclosed
US-11840560-B2 Prodrugs and uses thereof NOVO NORDISK A/S (DK) 2023-12-12 US disclosed
US-11840560-B2 Prodrugs and uses thereof NOVO NORDISK A/S (DK) 2023-12-12 US disclosed
WO-2023139187-A1 GLP-1/GIP RECEPTOR CO-AGONIST PRODRUGS AND USES THEREOF NOVO NORDISK A/S (DK) 2023-07-27 WO disclosed
WO-2023139187-A1 GLP-1/GIP RECEPTOR CO-AGONIST PRODRUGS AND USES THEREOF NOVO NORDISK A/S (DK) 2023-07-27 WO disclosed
US-20230227521-A1 PRODRUGS AND USES THEREOF NOVO NORDISK A/S (DK) 2023-07-20 US disclosed
US-20230227521-A1 PRODRUGS AND USES THEREOF NOVO NORDISK A/S (DK) 2023-07-20 US disclosed
US-20230227521-A1 PRODRUGS AND USES THEREOF NOVO NORDISK A/S (DK) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11840560-B2 Prodrugs and uses thereof GIPR, GLP1R, GRPR NOD1 687/4885EPHX1 2957/4885GPR84 69/4885
US-20230227521-A1 PRODRUGS AND USES THEREOF GIPR, GLP1R, GRPR NOD1 687/4885EPHX1 2957/4885GPR84 69/4885
US-20240083965-A1 PRODRUGS AND USES THEREOF GIPR, GLP1R, GRPR NOD1 687/4885EPHX1 2957/4885GPR84 69/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.