SCHEMBL25849917

SCHEMBL25849917

CC(C)C(=O)CNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCC(=O)O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ NOD1 Q9Y239 7/20 0.56
▸ GLP1R P43220 8/20 0.43
▸ GNPAT O15228 1/20 0.43
▸ SLC6A5 Q9Y345 1/20 0.43
▸ FOLH1 Q04609 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20215722 0.89 NOD1 (0.50) NOD1GLP1R
SCHEMBL24276030 0.89 NOD1 (0.45) NOD1GLP1R
SCHEMBL19879817 0.89 NOD1 (0.45) NOD1GLP1R
SCHEMBL25977900 0.89 NOD1 (0.61) NOD1GNPATSLC6A5FOLH1
SCHEMBL21937170 0.89 NOD1 (0.61) NOD1GNPATSLC6A5FOLH1
SCHEMBL25850237 0.89 NOD1 (0.61) NOD1GNPATSLC6A5FOLH1
SCHEMBL21937004 0.89 NOD1 (0.61) NOD1GNPATSLC6A5FOLH1
SCHEMBL21937167 0.89 NOD1 (0.61) NOD1GNPATSLC6A5FOLH1
SCHEMBL21937168 0.89 NOD1 (0.61) NOD1GNPATSLC6A5FOLH1
SCHEMBL25976528 0.89 NOD1 (0.61) NOD1GNPATSLC6A5FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11840560-B2 Prodrugs and uses thereof NOVO NORDISK A/S (DK) 2023-12-12 — — US disclosed
US-20230227521-A1 PRODRUGS AND USES THEREOF NOVO NORDISK A/S (DK) 2023-07-20 — — US disclosed
US-20230227521-A1 PRODRUGS AND USES THEREOF NOVO NORDISK A/S (DK) 2023-07-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11840560-B2 Prodrugs and uses thereof GIPR, GLP1R, GRPR NOD1 687/4885GLP1R 2/4885GNPAT 983/4885
US-20230227521-A1 PRODRUGS AND USES THEREOF GIPR, GLP1R, GRPR NOD1 687/4885GLP1R 2/4885GNPAT 983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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