SCHEMBL25850010

SCHEMBL25850010

Cc1ccc2c(c1)C(=O)/C(=C\c1ccc3c4c(ccc3c1)N(c1ccccc1)c1ccc(-c3c(C(C)C)cccc3C(C)C)cc1C4(C)C)C2=O

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 2/20 0.34
CSNK2B P67870 2/20 0.34
CSNK2A1 P68400 2/20 0.34
CSNK2A3 Q8NEV1 2/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
GAA P10253 2/20 0.33
ALDH1A1 P00352 3/20 0.31
PKM P14618 1/20 0.31
HTT P42858 1/20 0.31
MAPT P10636 2/20 0.30
NPC1 O15118 1/20 0.30
CRHBP P24387 1/20 0.30
RAB9A P51151 1/20 0.30
CRHR2 Q13324 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
KDM4E B2RXH2 1/20 0.30
KDR P35968 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25851420 0.94 MAPT (0.33) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL25851423 0.92 LCK (0.36) CSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL25850007 0.91 CSNK2A2 (0.35) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL25850013 0.91 CSNK2A2 (0.35) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL25850011 0.91 MEN1 (0.36) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL25850001 0.90 CSNK2A2 (0.37) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL25850017 0.90 CSNK2A2 (0.34) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL25850021 0.90 CSNK2A2 (0.40) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL25850026 0.88 CSNK2A2 (0.39) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL25849959 0.88 CSNK2A2 (0.40) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed