SCHEMBL25850011

SCHEMBL25850011

Cc1ccc2c(c1)C(=O)/C(=C\c1ccc3c(c1)C(C)(C)c1cc(-c4c(C(C)C)cccc4C(C)C)ccc1N3c1ccccc1)C2=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.36
KMT2A Q03164 8/20 0.36
GAA P10253 3/20 0.36
CSNK2A2 P19784 2/20 0.35
CSNK2B P67870 2/20 0.35
CSNK2A1 P68400 2/20 0.35
CSNK2A3 Q8NEV1 2/20 0.35
ALDH1A1 P00352 10/20 0.33
MAPT P10636 5/20 0.33
NPSR1 Q6W5P4 3/20 0.33
NPC1 O15118 1/20 0.33
CRHBP P24387 1/20 0.33
RAB9A P51151 1/20 0.33
CRHR2 Q13324 1/20 0.33
KDM4E B2RXH2 5/20 0.33
HTT P42858 3/20 0.33
KDR P35968 1/20 0.33
PKM P14618 1/20 0.33
ELANE P08246 1/20 0.32
HPGD P15428 5/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25850010 0.91 CSNK2A2 (0.34) MEN1KMT2AGAACSNK2A2CSNK2B
SCHEMBL25851426 0.91 MEN1 (0.33) MEN1KMT2ACSNK2A2CSNK2BCSNK2A1
SCHEMBL25850014 0.90 MEN1 (0.37) MEN1KMT2AGAACSNK2A2CSNK2B
SCHEMBL25850008 0.89 CSNK2A2 (0.38) MEN1KMT2AGAACSNK2A2CSNK2B
SCHEMBL25850019 0.89 MEN1 (0.36) MEN1KMT2AGAACSNK2A2CSNK2B
SCHEMBL25850003 0.88 CSNK2A2 (0.39) MEN1KMT2AGAACSNK2A2CSNK2B
SCHEMBL25850024 0.87 CSNK2A2 (0.43) MEN1KMT2AGAACSNK2A2CSNK2B
SCHEMBL25850009 0.87 MAPT (0.33) MEN1KMT2AGAAALDH1A1MAPT
SCHEMBL25849960 0.86 CSNK2A2 (0.42) MEN1KMT2AGAACSNK2A2CSNK2B
SCHEMBL25850028 0.86 CSNK2A2 (0.42) MEN1KMT2AGAACSNK2A2CSNK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed