SCHEMBL25850032

SCHEMBL25850032

Cc1ccc2c(c1)C(=O)/C(=C\c1ccc3c(c1)C1(c4ccccc4-c4ccccc41)c1ccccc1N3c1ccccc1)C2=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 1/20 0.40
CSNK2B P67870 1/20 0.40
CSNK2A1 P68400 1/20 0.40
CSNK2A3 Q8NEV1 1/20 0.40
ELANE P08246 1/20 0.39
ALDH1A1 P00352 10/20 0.39
KMT2A Q03164 9/20 0.39
MAPT P10636 8/20 0.39
MEN1 O00255 7/20 0.39
KDM4E B2RXH2 4/20 0.39
NPSR1 Q6W5P4 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
MITF O75030 1/20 0.38
LMNA P02545 1/20 0.38
PLA2G1B P04054 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
NPC1 O15118 1/20 0.38
CRHBP P24387 1/20 0.38
RAB9A P51151 1/20 0.38
CRHR2 Q13324 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22825997 0.89 LCK (0.45) ALDH1A1KMT2AMAPTMEN1KDM4E
SCHEMBL25849960 0.89 CSNK2A2 (0.42) CSNK2A2CSNK2BCSNK2A1CSNK2A3ELANE
SCHEMBL25850031 0.88 CSNK2A2 (0.36) CSNK2A2CSNK2BCSNK2A1CSNK2A3ELANE
SCHEMBL25851496 0.88 MAPT (0.39) ALDH1A1KMT2AMAPTMEN1KDM4E
SCHEMBL22825606 0.88 MAPT (0.39) ALDH1A1KMT2AMAPTMEN1KDM4E
SCHEMBL25850024 0.85 CSNK2A2 (0.43) CSNK2A2CSNK2BCSNK2A1CSNK2A3ELANE
SCHEMBL22826057 0.84 MAPT (0.39) ALDH1A1KMT2AMAPTMEN1KDM4E
SCHEMBL22825994 0.83 MAPT (0.39) ALDH1A1KMT2AMAPTMEN1KDM4E
SCHEMBL22825599 0.83 LCK (0.38) CSNK2A2CSNK2BCSNK2A1CSNK2A3ALDH1A1
SCHEMBL25451891 0.83 MAPT (0.43) ALDH1A1KMT2AMAPTMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed