SCHEMBL25850024

SCHEMBL25850024

Cc1ccc2c(c1)C(=O)/C(=C\c1ccc3c(c1)C(C)(C)c1cc(C)ccc1N3c1ccccc1)C2=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 1/20 0.43
CSNK2B P67870 1/20 0.43
CSNK2A1 P68400 1/20 0.43
CSNK2A3 Q8NEV1 1/20 0.43
KMT2A Q03164 8/20 0.41
MEN1 O00255 6/20 0.41
GAA P10253 3/20 0.41
ELANE P08246 1/20 0.40
ALDH1A1 P00352 9/20 0.39
MAPT P10636 7/20 0.39
KDM4E B2RXH2 4/20 0.39
NPSR1 Q6W5P4 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HSD17B10 Q99714 1/20 0.38
MITF O75030 1/20 0.38
LMNA P02545 1/20 0.38
PLA2G1B P04054 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
NPC1 O15118 1/20 0.38
CRHBP P24387 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849960 0.97 CSNK2A2 (0.42) CSNK2A2CSNK2BCSNK2A1CSNK2A3KMT2A
SCHEMBL25851462 0.93 CSNK2A2 (0.39) CSNK2A2CSNK2BCSNK2A1CSNK2A3KMT2A
SCHEMBL25850003 0.93 CSNK2A2 (0.39) CSNK2A2CSNK2BCSNK2A1CSNK2A3KMT2A
SCHEMBL25850028 0.92 CSNK2A2 (0.42) CSNK2A2CSNK2BCSNK2A1CSNK2A3KMT2A
SCHEMBL25850008 0.90 CSNK2A2 (0.38) CSNK2A2CSNK2BCSNK2A1CSNK2A3KMT2A
SCHEMBL25850014 0.90 MEN1 (0.37) CSNK2A2CSNK2BCSNK2A1CSNK2A3KMT2A
SCHEMBL25451891 0.89 MAPT (0.43) KMT2AMEN1ALDH1A1MAPTKDM4E
SCHEMBL25850021 0.88 CSNK2A2 (0.40) CSNK2A2CSNK2BCSNK2A1CSNK2A3KMT2A
SCHEMBL25850019 0.88 MEN1 (0.36) CSNK2A2CSNK2BCSNK2A1CSNK2A3KMT2A
SCHEMBL25850011 0.87 MEN1 (0.36) CSNK2A2CSNK2BCSNK2A1CSNK2A3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed