SCHEMBL25850559

SCHEMBL25850559

BN1c2ccccc2C(C)(C)c2cc(/C=C3/C(=O)N(CC)C(=O)C(C#N)=C3C)ccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.33
ALDH1A1 P00352 7/20 0.33
MEN1 O00255 6/20 0.33
KMT2A Q03164 6/20 0.33
L3MBTL1 Q9Y468 4/20 0.33
MAPK1 P28482 3/20 0.33
KDM4E B2RXH2 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
GPR55 Q9Y2T6 1/20 0.33
POLB P06746 1/20 0.32
HPGD P15428 1/20 0.32
BLM P54132 1/20 0.32
MCL1 Q07820 1/20 0.32
USP2 O75604 1/20 0.31
GAA P10253 3/20 0.31
LMNA P02545 2/20 0.31
HTT P42858 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
EP300 Q09472 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849720 0.92 MAPT (0.35) MAPTALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL25850554 0.89 MAPT (0.30) MAPTALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL25849719 0.81 MEN1 (0.32) MAPTALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL25849722 0.77 MEN1 (0.36) MAPTALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL25850569 0.76 NR1H4 (0.47) MAPTALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL10134153 0.73 MAPT (0.40) MAPTALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL25850600 0.71 LCK (0.37) MAPTALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL22177565 0.70 MAPT (0.38) MAPTALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL25849998 0.69 CSNK2A2 (0.40) MAPTALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL22849323 0.69 PGR (0.36) MAPTALDH1A1MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed