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SCHEMBL25850639

SCHEMBL25850639

c1ccc(C2(c3ccccc3)c3ccccc3Oc3ccc(-c4ccc5c(c4)C4(c6ccccc6-5)c5ccccc5-c5ccc6ccccc6c54)cc32)cc1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ OPRK1 P41145 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25866634 1.00 PDK2 (0.32) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL25871253 0.99 PDK2 (0.33) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL25872645 0.98 PDK2 (0.33) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL25850395 0.96 KDM4E (0.33) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL25866554 0.95 KDM4E (0.33) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL25866639 0.95 DHFR (0.31) PDK2
SCHEMBL25850637 0.94 PDK2 (0.31) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL25858516 0.94 PDK2 (0.33) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL25865152 0.93 PDK2 (0.32) PDK2
SCHEMBL25866175 0.93 KDM4E (0.32) PDK2KDM4EMEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023120714-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2023-06-29 — — WO disclosed