SCHEMBL25850800

SCHEMBL25850800

CC1(C)c2cc(C=C3C(=O)c4cc5ccccc5cc4C3=O)ccc2Nc2ccc(-c3c(F)cccc3P)cc21

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PGR P06401 13/20 0.35
MAPT P10636 3/20 0.33
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
RET P07949 1/20 0.31
LCK P06239 1/20 0.31
KMT2A Q03164 2/20 0.31
USP2 O75604 1/20 0.31
PKM P14618 1/20 0.31
KDR P35968 2/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849763 0.83 MAPT (0.33) PGRMAPTALDH1A1KDM4EGAA
SCHEMBL25849761 0.75 KDM4E (0.34) MAPTALDH1A1KDM4EGAA
SCHEMBL25851449 0.75 KDM4E (0.32) MAPTALDH1A1KDM4EKMT2A
SCHEMBL25849753 0.73 RET (0.36) MAPTALDH1A1KDM4EGAARET
SCHEMBL25850749 0.72 GRIA1 (0.35) PGRMAPTALDH1A1RETKMT2A
SCHEMBL25850019 0.72 MEN1 (0.36) MAPTALDH1A1KDM4EGAAKMT2A
SCHEMBL25849765 0.71 CREBBP (0.32)
SCHEMBL25849749 0.71 BCL2 (0.32) MAPTALDH1A1KDM4EGAALCK
SCHEMBL25850676 0.70 BCL2 (0.32) MAPTALDH1A1KDM4EGAALCK
SCHEMBL22177616 0.69 BCL2 (0.36) MAPTALDH1A1KDM4EGAALCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed