SCHEMBL25850749

SCHEMBL25850749

Cc1cccc(C)c1-c1ccc2c(c1)C(C)(C)c1cc(C=C3C(=O)c4cc5ccccc5cc4C3=O)sc1N2

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GRIA1 P42261 2/20 0.35
CACNG8 Q8WXS5 2/20 0.35
RET P07949 1/20 0.35
PGR P06401 10/20 0.33
ERBB2 P04626 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33
HPGD P15428 1/20 0.33
RECQL P46063 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDR P35968 2/20 0.31
BRD4 O60885 3/20 0.31
NR3C1 P04150 1/20 0.30
NR3C2 P08235 1/20 0.30
AR P10275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25850536 0.84 PDK2 (0.38) RETALDH1A1MAPTTHRBHPGD
SCHEMBL25850838 0.82 EGFR (0.35) ERBB2ALDH1A1MAPTTHRBHPGD
SCHEMBL25849755 0.80 POLB (0.33) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL25849753 0.76 RET (0.36) RETALDH1A1MAPTKMT2AKDR
SCHEMBL25850805 0.76 ALDH1A1 (0.30) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL25849750 0.75 ALDH1A1 (0.32) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL25850800 0.72 PGR (0.35) RETPGRALDH1A1MAPTKMT2A
SCHEMBL25849765 0.72 CREBBP (0.32)
SCHEMBL25849749 0.70 BCL2 (0.32) ALDH1A1MAPTKMT2A
SCHEMBL23128478 0.69 MAPT (0.42) PGRALDH1A1MAPTTHRBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed