Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL2585089

CCCC[C@]1(CC)CS(O)(O)c2cc(CNC(=O)CCS(=O)(=O)O)c(OC)cc2[C@@H](c2ccccc2)N1.N

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL2585080 1.00 SLC10A2 (0.85) SLC10A2
Ammonia Solution, Strong SCHEMBL2585082 0.93 SLC10A2 (0.99) SLC10A2
Ammonia Solution, Strong SCHEMBL2585099 0.93 SLC10A2 (0.99) SLC10A2
SCHEMBL14666030 0.92 SLC10A2 (1.00) SLC10A2
SCHEMBL2590078 0.92 SLC10A2 (0.86) SLC10A2
SCHEMBL2585331 0.90 SLC10A2 (0.71) SLC10A2
SCHEMBL14659287 0.89 SLC10A2 (0.77) SLC10A2
SCHEMBL2592819 0.89 SLC10A2 (0.86) SLC10A2
Ammonia Solution, Strong SCHEMBL2590970 0.89 SLC10A2 (0.85) SLC10A2
Ammonia Solution, Strong SCHEMBL2590974 0.89 SLC10A2 (0.85) SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2563122-B1 CHEMICAL COMPOUNDS GLAXOSMITHKLINE LLC (US) 2016-06-08 EP disclosed
EP-2563122-A1 CHEMICAL COMPOUNDS Glaxosmithkline LLC (US) 2013-03-06 EP disclosed
WO-2011137135-A1 CHEMICAL COMPOUNDS GLAXOSMITHKLINE LLC (US) 2011-11-03 WO disclosed