SCHEMBL25850991

SCHEMBL25850991

Cc1cccc(Oc2cc(Oc3cccc(C)n3)cc(Oc3cccc(C#N)n3)c2)n1

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 1/20 0.39
GRM5 P41594 4/20 0.39
GABRA5 P31644 1/20 0.39
P2RX3 P56373 4/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Amelenodor SCHEMBL22061849 0.85 CCR1 (0.44) GRM5
SCHEMBL30689391 0.81 LMNA (0.50)
SCHEMBL16483429 0.79 FFAR4 (0.47) FFAR4
SCHEMBL1680654 0.78 SMN1; SMN2 (0.47) GABRA5P2RX3
SCHEMBL129516 0.77
SCHEMBL29843739 0.77
SCHEMBL22009636 0.77 PPARG (0.40) GRM5
SCHEMBL22009626 0.77 BRD4 (0.42) GRM5
SCHEMBL22009633 0.77 MEN1 (0.53) GRM5
SCHEMBL29716175 0.77 BRD4 (0.42) GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4212513-A1 1,3,5-TRIS(6-METHYLPYRIDIN-2-YLOXY)BENZENE DERIVATIVES AND RELATED COMPOUNDS AS NLRX1 LIGANDS FOR TREATING INFLAMMATORY DISEASES LANDOS BIOPHARMA, INC. (US) 2023-07-19 EP disclosed