SCHEMBL2585148

SCHEMBL2585148

Cc1ccc(-n2c(-c3ccc(-c4ccc(-c5nc6c7ccccc7c7ccccc7c6n5-c5ccc(C)cc5)cc4)cc3)nc3c4ccccc4c4ccccc4c32)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.49
NPSR1 Q6W5P4 2/20 0.46
RAB9A P51151 1/20 0.46
LMNA P02545 1/20 0.46
GAA P10253 1/20 0.46
DHFR P00374 1/20 0.43
MAPT P10636 2/20 0.42
RXFP1 Q9HBX9 2/20 0.41
MDM2 Q00987 1/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HSP90AA1 P07900 1/20 0.40
HPGD P15428 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
KDM4E B2RXH2 2/20 0.39
PPARG P37231 1/20 0.39
NCOA2 Q15596 1/20 0.39
NCOA1 Q15788 1/20 0.39
ADORA3 P0DMS8 1/20 0.38
ADORA2A P29274 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1696798 0.94 ALDH1A1 (0.52) ALDH1A1NPSR1RAB9ALMNAGAA
SCHEMBL27412107 0.94 ALDH1A1 (0.49) ALDH1A1NPSR1RAB9ALMNAGAA
SCHEMBL2586996 0.92 MAPT (0.52) ALDH1A1NPSR1RAB9ALMNAGAA
SCHEMBL31109976 0.91 MEN1 (0.48) ALDH1A1NPSR1RAB9ALMNAGAA
SCHEMBL21195750 0.91 MEN1 (0.48) ALDH1A1NPSR1RAB9ALMNAGAA
SCHEMBL2585614 0.89 MEN1 (0.46) ALDH1A1NPSR1RAB9ALMNAGAA
SCHEMBL30507756 0.89 MEN1 (0.46) ALDH1A1NPSR1RAB9ALMNAGAA
SCHEMBL762904 0.88 ALDH1A1 (0.45) ALDH1A1NPSR1RAB9ALMNAGAA
SCHEMBL762897 0.88 ALDH1A1 (0.43) ALDH1A1NPSR1RAB9ALMNAGAA
SCHEMBL29321146 0.88 ALDH1A1 (0.45) ALDH1A1NPSR1RAB9ALMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3639308-B1 ORGANIC ELECTROLUMINESCENT DEVICE SAMSUNG DISPLAY CO LTD (KR) 2023-07-26 EP disclosed
EP-3809479-B1 ORGANIC ELECTROLUMINESCENT DEVICE EMITTING BLUE LIGHT SAMSUNG DISPLAY CO LTD (KR) 2023-07-12 EP disclosed
US-11165035-B2 Organic electroluminescent device emitting blue light CYNORA GMBH (DE) 2021-11-02 US disclosed
EP-3483156-B1 ORGANIC MOLECUES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-09-16 EP disclosed
EP-3613744-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-02-26 EP disclosed
US-20190177303-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-06-13 US disclosed
EP-3483156-A1 ORGANIC MOLECUES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-05-15 EP disclosed
US-9917270-B1 Organic electroluminescent device having an exciton quenching layer CYNORA GMBH (DE) 2018-03-13 US disclosed
US-9917270-B1 Organic electroluminescent device having an exciton quenching layer CYNORA GMBH (DE) 2018-03-13 US disclosed
US-9062368-B2 Method of monitoring photoactive organic molecules in-situ during gas-phase deposition of the photoactive organic molecules THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2015-06-23 US disclosed
US-8048542-B2 Bis-phenanthroimidazolyl compound and electroluminescent device using the same NATIONAL TSING HUA UNIVERSITY (TW) 2011-11-01 US disclosed
US-20100253208-A1 BIS-PHENANTHROIMIDAZOLYL COMPOUND AND ELECTROLUMINESCENT DEVICE USING THE SAME E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100253208-A1 BIS-PHENANTHROIMIDAZOLYL COMPOUND AND ELECTROLUMINESCENT DEVICE USING THE SAME SLC43A3, SLC29A1, SLC29A2 ALDH1A1 927/4885NPSR1 1614/4885RAB9A 621/4885
US-20190177303-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, ORC3, OR51E2 ALDH1A1 542/4885NPSR1 1737/4885RAB9A 3768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.