Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 7/20 | 0.59 |
| ▸ | CHRNB4 | P30926 | 7/20 | 0.59 |
| ▸ | CHRNA3 | P32297 | 7/20 | 0.59 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.59 |
| ▸ | CCR6 | P51684 | 2/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13778339 | 0.90 | CHRNB2 (0.55) | CHRNB2CHRNB4CHRNA3CHRNA4CCR6 | |
| SCHEMBL20694289 | 0.81 | AR (0.45) | CHRNB2CHRNB4CHRNA3CHRNA4AR | |
| SCHEMBL16938289 | 0.81 | CHRNB2 (0.59) | CHRNB2CHRNB4CHRNA3CHRNA4CYP3A4 | |
| SCHEMBL5404714 | 0.81 | CHRNB4 (0.54) | CHRNB2CHRNB4CHRNA3CHRNA4CCR6 | |
| SCHEMBL17796709 | 0.81 | CCR6 (0.42) | CHRNB2CHRNB4CHRNA3CHRNA4CCR6 | |
| SCHEMBL23707244 | 0.81 | CCR6 (0.42) | CHRNB2CHRNB4CHRNA3CHRNA4CCR6 | |
| SCHEMBL15205522 | 0.81 | CHRNB2 (0.59) | CHRNB2CHRNB4CHRNA3CHRNA4CCR6 | |
| SCHEMBL25855696 | 0.80 | CCR6 (0.55) | CHRNB2CHRNB4CHRNA3CHRNA4CCR6 | |
| SCHEMBL24528582 | 0.78 | CHRNB2 (0.57) | CHRNB2CHRNB4CHRNA3CHRNA4CYP3A4 | |
| SCHEMBL26951386 | 0.78 | CHRNB2 (0.54) | CHRNB2CHRNB4CHRNA3CHRNA4CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107723-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |