Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 19/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25852058 | 0.93 | MAPK1 (0.53) | MAPK1 | |
| SCHEMBL25856932 | 0.90 | MAPK1 (0.56) | MAPK1 | |
| SCHEMBL25853244 | 0.88 | MAPK1 (0.51) | MAPK1 | |
| SCHEMBL25852278 | 0.86 | MAPK1 (0.53) | MAPK1 | |
| SCHEMBL25833943 | 0.86 | MAPK1 (0.56) | MAPK1 | |
| SCHEMBL25857373 | 0.85 | MAPK1 (0.53) | MAPK1 | |
| SCHEMBL25857520 | 0.84 | MAPK1 (0.46) | MAPK1 | |
| SCHEMBL25971078 | 0.84 | MAPK1 (0.53) | MAPK1 | |
| SCHEMBL21557654 | 0.83 | MAPK1 (0.53) | MAPK1 | |
| SCHEMBL21557727 | 0.83 | MAPK1 (0.49) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023135233-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV DISCOVERY (FR) | 2023-07-20 | — | — | WO | disclosed |