Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 19/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25856932 | 0.92 | MAPK1 (0.56) | MAPK1 | |
| SCHEMBL25852706 | 0.88 | MAPK1 (0.51) | MAPK1 | |
| SCHEMBL25852278 | 0.88 | MAPK1 (0.53) | MAPK1 | |
| SCHEMBL25852058 | 0.88 | MAPK1 (0.53) | MAPK1 | |
| SCHEMBL25852436 | 0.85 | MAPK1 (0.51) | MAPK1 | |
| SCHEMBL25833943 | 0.84 | MAPK1 (0.56) | MAPK1 | |
| SCHEMBL21557661 | 0.83 | MAPK1 (0.52) | MAPK1 | |
| SCHEMBL25852539 | 0.82 | MAPK1 (0.57) | MAPK1 | |
| SCHEMBL25853245 | 0.82 | MAPK1 (0.74) | MAPK1 | |
| SCHEMBL25853736 | 0.82 | MAPK1 (0.58) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023135233-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV DISCOVERY (FR) | 2023-07-20 | — | — | WO | disclosed |