Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 18/20 | 0.54 |
| ▸ | CA2 | P00918 | 18/20 | 0.54 |
| ▸ | CA9 | Q16790 | 15/20 | 0.52 |
| ▸ | CA12 | O43570 | 5/20 | 0.50 |
| ▸ | CA7 | P43166 | 5/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.50 |
| ▸ | CA3 | P07451 | 4/20 | 0.50 |
| ▸ | CA4 | P22748 | 4/20 | 0.50 |
| ▸ | CA6 | P23280 | 4/20 | 0.50 |
| ▸ | CA5A | P35218 | 4/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2581605 | 0.98 | CA1 (0.52) | CA1CA2CA9CA12CA7 | |
| SCHEMBL29166175 | 0.86 | CA1 (0.61) | CA1CA2CA9CA12CA7 | |
| SCHEMBL29166512 | 0.84 | CA1 (0.65) | CA1CA2CA9CA12CA7 | |
| SCHEMBL18063462 | 0.83 | LMNA (0.48) | CA1CA2CA9CA12CA7 | |
| SCHEMBL29166293 | 0.82 | CA1 (0.67) | CA1CA2CA9CA12CA7 | |
| SCHEMBL29166463 | 0.82 | CA1 (0.67) | CA1CA2CA9CA12CA7 | |
| SCHEMBL29166904 | 0.82 | CA1 (0.67) | CA1CA2CA9CA12CA7 | |
| SCHEMBL18086670 | 0.82 | CA1 (0.50) | CA1CA2CA9CA12CA7 | |
| SCHEMBL29166240 | 0.82 | CA1 (0.67) | CA1CA2CA9CA12CA7 | |
| SCHEMBL18086664 | 0.79 | CA1 (0.54) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |
| CN-107209146-B | Electrochemical gas sensor and electrolyte for electrochemical gas sensor | 德尔格安全股份两合公司 | 2024-03-12 | — | — | CN | disclosed |
| US-20130123135-A1 | Methods To Identify Modulators of TAS2R48 Receptors | GIVAUDAN SA (CH) | 2013-05-16 | — | — | US | disclosed |
| US-20130115624-A1 | Methods To Identify Modulators | GIVAUDAN S.A. (CH) | 2013-05-09 | — | — | US | disclosed |
| EP-2567229-A1 | METHODS TO IDENTIFY MODULATORS | Givaudan SA (CH) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011138455-A1 | METHODS TO IDENTIFY MODULATORS | GIVAUDAN SA (CH) | 2011-11-10 | — | — | WO | disclosed |
| US-20050245563-A1 | Chk-1 inhibitors | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-11-03 | — | — | US | disclosed |
| WO-2005028474-A2 | PYRAZOLOQUINOLINE DERIVATIVES AS CHK-1 INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245563-A1 | Chk-1 inhibitors | CHKA, CHKB, CHEK1 | CA1 4191/4885CA2 3170/4885CA9 3301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.