SCHEMBL25853454

SCHEMBL25853454

C=CC(=O)Oc1ccc2c(sc3c(OC)c(OC(=O)C=C)ccc32)c1F

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.34
TYMS P04818 1/20 0.33
THRB P10828 2/20 0.32
THRA P10827 1/20 0.32
MEN1 O00255 1/20 0.30
USP2 O75604 1/20 0.30
MAPT P10636 1/20 0.30
ALOX15 P16050 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25853782 0.92 TYMS (0.37) EGFRTYMSTHRBTHRAMEN1
SCHEMBL25853366 0.89 TYMS (0.39) EGFRTYMSTHRBTHRA
SCHEMBL25855454 0.87 THRB (0.34) EGFRTYMSTHRB
SCHEMBL25854859 0.86 THRB (0.34) EGFRTYMSTHRB
SCHEMBL25853664 0.86 TYMS (0.34) TYMSTHRBTHRAMEN1USP2
SCHEMBL25853852 0.85 TYMS (0.32) TYMSTHRBTHRA
SCHEMBL25853529 0.85 TYMS (0.32) TYMS
SCHEMBL25853371 0.84 TYMS (0.34) EGFRTYMSTHRBTHRA
SCHEMBL25853848 0.84 TYMS (0.32) TYMSTHRBTHRA
SCHEMBL25853455 0.83 ELANE (0.31) MEN1USP2MAPTALOX15KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134598-A1 POLYMERISABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134596-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed